Tobacco smoking is a major determinant of preventable morbidity and mortality worldwide.
More than a billion people smoke, and without major increases in cessation, at least half will …

Chronic heavy alcohol use impacts all major neurotransmitter systems and is associated
with multiple medical, psychiatric, and social problems. Available evidence‐based …

Importance The concurrent use of both tobacco and alcohol causes substantial disease and
early mortality, and smokers who drink heavily tend to be less successful in smoking …

This paper is the forty-fourth consecutive installment of the annual anthological review of
research concerning the endogenous opioid system, summarizing articles published during …

Aims To estimate recent trends in cigarette use and health insurance coverage for United
States adults with and without mental health and substance use disorders (MH/SUD) …

Objective Cannabis and alcohol co-use is highly prevalent and confers a host of risk factors
that outweigh those related to the use of either substance alone. However, few studies have …

Objective: Alcohol, tobacco, and cannabis are the three most frequently used drugs in the
United States and co-use is common. Alcohol, tobacco, and cannabis use has been …

Cigarette smoking and heavy alcohol drinking frequently cooccur. Nearly 20% of smokers
drink heavily, compared with 6.5% of nonsmokers, and heavy drinkers are 2–3 times more …

Abstract Background The US Food and Drug Administration identifies abstinence and the
absence of heavy drinking days as outcomes for pharmacotherapy trials for alcohol use …

Background There is a strong bidirectional relationship between the use of alcohol and
cigarettes which results in various challenges for treating those who co-use both …