A brief insight into the etiology, genetics, and immunology of polycystic ovarian syndrome (PCOS)

S Siddiqui, S Mateen, R Ahmad, S Moin - Journal of assisted reproduction …, 2022 - Springer
Polycystic ovarian syndrome (PCOS) is a prevailing endocrine and metabolic disorder
occurring in about 6–20% of females in reproductive age. Most symptoms of PCOS arise …

Therapeutic opportunities for pancreatic β-cell ER stress in diabetes mellitus

J Yong, JD Johnson, P Arvan, J Han… - Nature Reviews …, 2021 - nature.com
Diabetes mellitus is characterized by the failure of insulin-secreting pancreatic β-cells (or β-
cell death) due to either autoimmunity (type 1 diabetes mellitus) or failure to compensate for …

[HTML][HTML] The role of advanced glycation end products in aging and metabolic diseases: bridging association and causality

J Chaudhuri, Y Bains, S Guha, A Kahn, D Hall, N Bose… - Cell metabolism, 2018 - cell.com
Accumulation of advanced glycation end products (AGEs) on nucleotides, lipids, and
peptides/proteins are an inevitable component of the aging process in all eukaryotic …

Obesity, oxidative stress, adipose tissue dysfunction, and the associated health risks: causes and therapeutic strategies

P Manna, SK Jain - Metabolic syndrome and related disorders, 2015 - liebertpub.com
Obesity is gaining acceptance as a serious primary health burden that impairs the quality of
life because of its associated complications, including diabetes, cardiovascular diseases …

Antioxidant effects and mechanisms of medicinal plants and their bioactive compounds for the prevention and treatment of type 2 diabetes: an updated review

JO Unuofin, SL Lebelo - Oxidative medicine and cellular …, 2020 - Wiley Online Library
Diabetes mellitus is a metabolic disorder that majorly affects the endocrine gland, and it is
symbolized by hyperglycemia and glucose intolerance owing to deficient insulin secretory …

Diabetes, oxidative stress and therapeutic strategies

L Rochette, M Zeller, Y Cottin, C Vergely - Biochimica et Biophysica Acta …, 2014 - Elsevier
Background Diabetes has emerged as a major threat to health worldwide. Scope of Review
The exact mechanisms underlying the disease are unknown; however, there is growing …

Obesity-associated oxidative stress: strategies finalized to improve redox state

I Savini, MV Catani, D Evangelista, V Gasperi… - International journal of …, 2013 - mdpi.com
Obesity represents a major risk factor for a plethora of severe diseases, including diabetes,
cardiovascular disease, non-alcoholic fatty liver disease, and cancer. It is often …

[HTML][HTML] Role of vitamin D in ovarian physiology and its implication in reproduction: a systematic review

M Irani, Z Merhi - Fertility and sterility, 2014 - Elsevier
Objective To report an update on the role of vitamin D (VD) in ovarian physiology with a
focus on genes involved in steroidogenesis, follicular development, and ovarian reserve, as …

Uremic toxicity of advanced glycation end products in CKD

AEM Stinghen, ZA Massy, H Vlassara… - Journal of the …, 2016 - journals.lww.com
Advanced glycation end products (AGEs), a heterogeneous group of compounds formed by
nonenzymatic glycation reactions between reducing sugars and amino acids, lipids, or DNA …

Detection technologies for reactive oxygen species: fluorescence and electrochemical methods and their applications

S Duanghathaipornsuk, EJ Farrell, AC Alba-Rubio… - Biosensors, 2021 - mdpi.com
Reactive oxygen species (ROS) have been found in plants, mammals, and natural
environmental processes. The presence of ROS in mammals has been linked to the …