This review begins by briefly presenting the history of research on the chemical composition
and other parameters of cells of E. coli and S. enterica at different exponential growth rates …

Bacterial physiology is a branch of biology that aims to understand overarching principles of
cellular reproduction. Many important issues in bacterial physiology are inherently …

INTRODUCTION The generation of biological data is presenting us with one of the most
demanding analysis challenges the world has ever faced, not only in terms of storage and …

Culture-independent microbiome studies have increased our understanding of the
complexity and metabolic potential of microbial communities. However, to understand the …

Metagenomic sequencing increased our understanding of the role of the microbiome in
health and disease, yet it only provides a snapshot of a highly dynamic ecosystem. Here, we …

Protein concentrations are set by a complex interplay between gene-specific regulatory
processes and systemic factors, including cell volume and shared gene expression …

Schaechter et al.(121) first demonstrated that the macromolecular composition of the
bacterial cell was related to its metabolic activity and that RNA-containing particles were …

It is generally assumed that the allocation and synthesis of total cellular resources in
microorganisms are uniquely determined by the growth conditions. Adaptation to a new …

It is remarkable how robustly a bacterial species can maintain its preferred size. This
capacity is intimately related to control of the cell cycle: cell size and growth rate determine …

Isobiotic mice, with an identical stable microbiota composition, potentially allow models of
host-microbial mutualism to be studied over time and between different laboratories. To …