Introduction Implantable devices can be designed to release drugs to localized regions of
tissue at sustained and reliable rates. Advances in polymer engineering have led to the …

Despite the high success rate of autologous grafts in tympanic membrane repair, clinical
alternatives are required for the closure of unresponsive chronic perforations that can lead to …

Adult mammals are generally believed to have limited ability to regenerate complex tissues
and instead, repair wounds by forming scars. In humans and across mammalian species …

The ear drum, or tympanic membrane (TM), is a key component in the intricate relay that
transmits air‐borne sound to our fluid‐filled inner ear. Despite early belief that the …

The tympanic membrane (TM) is constantly in a state of vibrating. However, there is currently
a lack of drug-delivery scaffolds suitable for the dynamic environment of TM perforation. In …

Objective We compared the histological changes and hearing restoration during the healing
of acute total tympanic membrane (TM) perforations between Sprague–Dawley (SD) rats …

Objectives To systematically explore the differences in acoustic changes and healing
outcomes of tympanic membranes (TMs) with pars flaccida perforation (PFP) and pars tensa …

Objective The objective of this study was to compare the efficacy of ofloxacin ear drops,
vaseline gauze (VG) and dry gelfoam alone on the large traumatic perforations of tympanic …

BACKGROUND: Postoperative adhesion is an important complication after middle-ear
surgeries. Although many materials have been tried to prevent this complication, the use of …

Objective The aim of this study was to evaluate the effect of vaseline gauze (VG) patching on
the treatment of large traumatic perforation of tympanic membrane (TM). Material and …