Clinical detection of silicosis is currently dependent on radiological and lung function
abnormalities, both late manifestations of disease. Markers of prediction and early detection …

Pirfenidone, a broad-spectrum antifibrotic agent, is known to have efficacy in certain fibrotic
disease models, and is under clinical trials in patients with idiopathic pulmonary fibrosis. We …

Ethnopharmacological relevance In the theory of traditional Chinese medicine, pulmonary
fibrosis (PF) belongs to pulmonary arthralgia, which means blood stasis in lung tissue. The …

Background Colonic subepithelial myofibroblasts (cSEMFs) are mesenchymal cells with a
pivotal role in the pathophysiology of Crohn's disease (CD) fibrosis. Here, we demonstrate …

BACKGROUND: Bronchiolitis obliterans syndrome is the main long-term complication of
lung transplantation that limits survival of lung transplant patients. Its pathophysiologic …

间质性肺疾病是指以弥漫性肺泡单位慢性炎症和问质纤维化为主要病理特征的一大组疾病.
多种细胞因子构成的复杂的细胞因子网络在间质性肺疾病的发病机制中发挥重要作用. Th1/Th2 …

目的观察益气养阴方对大鼠肺间质纤维化模型肺组织形态结构及肿瘤坏死因子仅(TNF-α),
转化生长因子13 (TGF-131), γ 干扰素(IFN-γ) mRNA 水平的影响. 方法通过气管内滴注博莱霉素 …

Idiopathic pulmonary fibrosis (IPF) is being more frequently diagnosed in India, due to its
increased awareness, better availability of computed tomography (CT) and fiberoptic …

Excessive exposure to respirable particles of crystalline silica is an occupational health
problem in developing countries and can cause a variety of pulmonary diseases, such as …

Результаты рандомизированного проспективного мультицентрового контролируемого
клинического исследования Antoniou KM и соавт. с участием 50 пациентов показали …