[HTML][HTML] The pleiotropic neuroprotective effects of resveratrol in cognitive decline and Alzheimer's disease pathology: From antioxidant to epigenetic therapy
C Grinán-Ferré, A Bellver-Sanchis, V Izquierdo… - Ageing Research …, 2021 - Elsevier
While the elderly segment of the population continues growing in importance,
neurodegenerative diseases increase exponentially. Lifestyle factors such as nutrition …
neurodegenerative diseases increase exponentially. Lifestyle factors such as nutrition …
Oxidative damage in neurodegeneration: roles in the pathogenesis and progression of Alzheimer disease
M Perluigi, F Di Domenico… - Physiological …, 2024 - journals.physiology.org
Alzheimer disease (AD) is associated with multiple etiologies and pathological mechanisms,
among which oxidative stress (OS) appears as a major determinant. Intriguingly, OS arises …
among which oxidative stress (OS) appears as a major determinant. Intriguingly, OS arises …
[HTML][HTML] Mitochondrial dysfunction, oxidative stress, and neuroinflammation: Intertwined roads to neurodegeneration
Oxidative stress develops as a response to injury and reflects a breach in the cell's
antioxidant capacity. Therefore, the fine-tuning of reactive oxygen species (ROS) generation …
antioxidant capacity. Therefore, the fine-tuning of reactive oxygen species (ROS) generation …
PPARγ/PGC1α signaling as a potential therapeutic target for mitochondrial biogenesis in neurodegenerative disorders
S Jamwal, JK Blackburn, JD Elsworth - Pharmacology & Therapeutics, 2021 - Elsevier
Neurodegenerative diseases represent some of the most devastating neurological
disorders, characterized by progressive loss of the structure and function of neurons. Current …
disorders, characterized by progressive loss of the structure and function of neurons. Current …
DYRK1A inhibitors for disease therapy: Current status and perspectives
Dual-specificity tyrosine phosphorylation-regulated kinase 1 A (DYRK1A) is a conserved
protein kinase that plays essential roles in various biological processes. It is located in the …
protein kinase that plays essential roles in various biological processes. It is located in the …
Resveratrol and brain mitochondria: a review
FR Jardim, FT de Rossi, MX Nascimento… - Molecular …, 2018 - Springer
Abstract Resveratrol (3, 4', 5-trihydroxystilbene; C 14 H 12 O 3) is a polyphenolic phytoalexin
found in grapes, berries, peanuts, and wines. Resveratrol has been viewed as an …
found in grapes, berries, peanuts, and wines. Resveratrol has been viewed as an …
[HTML][HTML] Green tea catechins attenuate neurodegenerative diseases and cognitive deficits
Neurodegenerative diseases exert an overwhelming socioeconomic burden all around the
globe. They are mainly characterized by modified protein accumulation that might trigger …
globe. They are mainly characterized by modified protein accumulation that might trigger …
Resveratrol induces brain resilience against Alzheimer neurodegeneration through proteostasis enhancement
R Corpas, C Griñán-Ferré, E Rodríguez-Farré… - Molecular …, 2019 - Springer
Resveratrol is a natural compound that mimics the antioxidant and antiaging effects of
caloric restriction, mainly mediated through SIRT1, a deacetylase that induces longevity and …
caloric restriction, mainly mediated through SIRT1, a deacetylase that induces longevity and …
[图书][B] Nanomaterials for agriculture and forestry applications
Nanomaterials for Agriculture and Forestry Applications explores how major nanomaterials
are being specially used in the agriculture, forestry, and other associated sectors. Plants and …
are being specially used in the agriculture, forestry, and other associated sectors. Plants and …
[HTML][HTML] Are mitophagy enhancers therapeutic targets for Alzheimer's disease?
JA Pradeepkiran, A Hindle, S Kshirsagar… - Biomedicine & …, 2022 - Elsevier
Healthy mitochondria are essential for functional bioenergetics, calcium signaling, and
balanced redox homeostasis. Dysfunctional mitochondria are a central aspect of aging and …
balanced redox homeostasis. Dysfunctional mitochondria are a central aspect of aging and …