[HTML][HTML] The pleiotropic neuroprotective effects of resveratrol in cognitive decline and Alzheimer's disease pathology: From antioxidant to epigenetic therapy

C Grinán-Ferré, A Bellver-Sanchis, V Izquierdo… - Ageing Research …, 2021 - Elsevier
While the elderly segment of the population continues growing in importance,
neurodegenerative diseases increase exponentially. Lifestyle factors such as nutrition …

Oxidative damage in neurodegeneration: roles in the pathogenesis and progression of Alzheimer disease

M Perluigi, F Di Domenico… - Physiological …, 2024 - journals.physiology.org
Alzheimer disease (AD) is associated with multiple etiologies and pathological mechanisms,
among which oxidative stress (OS) appears as a major determinant. Intriguingly, OS arises …

[HTML][HTML] Mitochondrial dysfunction, oxidative stress, and neuroinflammation: Intertwined roads to neurodegeneration

A Picca, R Calvani, HJ Coelho-Junior, F Landi… - Antioxidants, 2020 - mdpi.com
Oxidative stress develops as a response to injury and reflects a breach in the cell's
antioxidant capacity. Therefore, the fine-tuning of reactive oxygen species (ROS) generation …

PPARγ/PGC1α signaling as a potential therapeutic target for mitochondrial biogenesis in neurodegenerative disorders

S Jamwal, JK Blackburn, JD Elsworth - Pharmacology & Therapeutics, 2021 - Elsevier
Neurodegenerative diseases represent some of the most devastating neurological
disorders, characterized by progressive loss of the structure and function of neurons. Current …

DYRK1A inhibitors for disease therapy: Current status and perspectives

T Liu, Y Wang, J Wang, C Ren, H Chen… - European journal of …, 2022 - Elsevier
Dual-specificity tyrosine phosphorylation-regulated kinase 1 A (DYRK1A) is a conserved
protein kinase that plays essential roles in various biological processes. It is located in the …

Resveratrol and brain mitochondria: a review

FR Jardim, FT de Rossi, MX Nascimento… - Molecular …, 2018 - Springer
Abstract Resveratrol (3, 4', 5-trihydroxystilbene; C 14 H 12 O 3) is a polyphenolic phytoalexin
found in grapes, berries, peanuts, and wines. Resveratrol has been viewed as an …

[HTML][HTML] Green tea catechins attenuate neurodegenerative diseases and cognitive deficits

O Afzal, MH Dalhat, ASA Altamimi, R Rasool… - Molecules, 2022 - mdpi.com
Neurodegenerative diseases exert an overwhelming socioeconomic burden all around the
globe. They are mainly characterized by modified protein accumulation that might trigger …

Resveratrol induces brain resilience against Alzheimer neurodegeneration through proteostasis enhancement

R Corpas, C Griñán-Ferré, E Rodríguez-Farré… - Molecular …, 2019 - Springer
Resveratrol is a natural compound that mimics the antioxidant and antiaging effects of
caloric restriction, mainly mediated through SIRT1, a deacetylase that induces longevity and …

[图书][B] Nanomaterials for agriculture and forestry applications

A Husen, M Jawaid - 2020 - books.google.com
Nanomaterials for Agriculture and Forestry Applications explores how major nanomaterials
are being specially used in the agriculture, forestry, and other associated sectors. Plants and …

[HTML][HTML] Are mitophagy enhancers therapeutic targets for Alzheimer's disease?

JA Pradeepkiran, A Hindle, S Kshirsagar… - Biomedicine & …, 2022 - Elsevier
Healthy mitochondria are essential for functional bioenergetics, calcium signaling, and
balanced redox homeostasis. Dysfunctional mitochondria are a central aspect of aging and …