Ventricular septal defects account for up to 40% of all congenital cardiac malformations. The
diagnosis encompasses a broad range of anomalies, including isolated defects and those …

Pulmonary arterial hypertension (PAH) is a common complication of congenital heart
disease (CHD), with most cases occurring in patients with congenital cardiac shunts. In …

A pulmonary hypertension (PH) registry (Spanish Registry of Pulmonary Arterial
Hypertension) was undertaken to analyse prevalence, incidence and survival of pulmonary …

Background: Eisenmenger syndrome describes congenital heart disease-associated severe
pulmonary hypertension accompanied by right-to-left shunting. The multicenter, double …

Rationale: Pulmonary arterial hypertension (PAH) is a medically incurable disease resulting
in death from right ventricular (RV) failure. Both pulmonary vascular and RV remodeling are …

Aims Iron deficiency is common in patients with Eisenmenger syndrome (ES). This study
aimed at evaluating (i) whether iron deficiency is related with adverse outcome,(ii) the …

Congenital heart disease (CHD), the most common inborn defect, affects approximately 1%
of all newborns worldwide. Advances in its diagnosis and treatment have led to a dramatic …

Introduction: Pulmonary hypertension (PH) is a common complication in patients with
congenital heart disease (CHD), aggravating the natural, post-operative, or post …

OBJECTIVE: To determine the frequence and profile of congenital heart defects in Down
syndrome patients referred to a pediatric cardiologic center, considering the age of referral …

The genetic abnormalities associated with D own syndrome (DS) are still being identified.
Few studies have examined the roles of CRELD1 and GATA4 in cardiac abnormalities or …