Clinical relevance of hepatitis B viral mutations
CM Hunt, JM McGill, MI Allen, LD Condreay - Hepatology, 2000 - journals.lww.com
One third of the global population has been acutely infected with hepatitis B virus (HBV);
less than 1% of patients with acute infection will develop fulminant hepatitis. 1 Approximately …
less than 1% of patients with acute infection will develop fulminant hepatitis. 1 Approximately …
Hepatitis B e antigen-negative chronic hepatitis B: natural history and treatment
SJ Hadziyannis… - Seminars in liver …, 2006 - thieme-connect.com
Hepatitis B e antigen (HBeAg)-negative chronic hepatitis B evolves in the natural history of
chronic hepatitis B virus (HBV) infection linked with selection of nonproducing HBeAg but …
chronic hepatitis B virus (HBV) infection linked with selection of nonproducing HBeAg but …
A new genotype of hepatitis B virus: complete genome and phylogenetic relatedness
L Stuyver, S De Gendt, C Van Geyt… - Journal of general …, 2000 - microbiologyresearch.org
The hepatitis B virus (HBV) genotype was determined in a total of 121 plasma samples
collected in France and the US from patients chronically infected with HBV. HBV genotype A …
collected in France and the US from patients chronically infected with HBV. HBV genotype A …
Associations between hepatitis B virus genotype and mutants and the risk of hepatocellular carcinoma
HI Yang, SH Yeh, PJ Chen, UH Iloeje… - Journal of the …, 2008 - academic.oup.com
Background The risk of hepatocellular carcinoma (HCC) increases with increasing level of
hepatitis B virus (HBV) in serum (viral load). However, it is unclear whether genetic …
hepatitis B virus (HBV) in serum (viral load). However, it is unclear whether genetic …
Adefovir dipivoxil for the treatment of hepatitis B e antigen–negative chronic hepatitis B
SJ Hadziyannis, NC Tassopoulos… - … England Journal of …, 2003 - Mass Medical Soc
Background Adefovir dipivoxil, a nucleotide analogue, demonstrated clinically significant
antiviral activity in patients with chronic hepatitis B in phase 1 and 2 clinical trials. Methods …
antiviral activity in patients with chronic hepatitis B in phase 1 and 2 clinical trials. Methods …
Virologic and histologic features of chronic hepatitis B virus-infected asymptomatic patients with persistently normal ALT
Background & Aims: There is a paucity of data on hepatitis B virus (HBV) DNA levels and
histologic lesions in patients with chronic HBV (CHBV) infection and persistently normal …
histologic lesions in patients with chronic HBV (CHBV) infection and persistently normal …
Influence of hepatitis B virus genotype on the long-term outcome of chronic hepatitis B in western patients
JM Sánchez-Tapias, J Costa, A Mas, M Bruguera… - Gastroenterology, 2002 - Elsevier
Background & Aims: The aim of this study was to investigate if the variable outcome of
chronic hepatitis B may be related to hepatitis B virus (HBV) genotype. Methods: The clinical …
chronic hepatitis B may be related to hepatitis B virus (HBV) genotype. Methods: The clinical …
[PDF][PDF] Efficacy of lamivudine in patients with hepatitis B e antigen–negative/hepatitis B virus DNA–positive (precore mutant) chronic hepatitis befficacy of lamivudine in …
NC Tassopoulos, R Volpes, G Pastore… - …, 1999 - Wiley Online Library
This placebo controlled, double‐blind study evaluated the efficacy and safety of lamivudine
in patients with hepatitis B e antigen (HBeAg)‐negative/hepatitis B virus (HBV) DNA …
in patients with hepatitis B e antigen (HBeAg)‐negative/hepatitis B virus (HBV) DNA …
Genotypes, nt 1858 variants, and geographic origin of hepatitis B virus—large-scale analysis using a new genotyping method
M Lindh, AS Andersson, A Gusdal - The Journal of infectious …, 1997 - academic.oup.com
The nucleotide at position 1858 of hepatitis B virus has importance in chronic hepatitis B
(HB) because a cytosine at nt 1858 effectively prevents virus escape through the precore …
(HB) because a cytosine at nt 1858 effectively prevents virus escape through the precore …
Core promoter mutations and genotypes in relation to viral replication and liver damage in East Asian hepatitis B virus carriers
M Lindh, C Hannoun, AP Dhillon… - The Journal of …, 1999 - academic.oup.com
Virus load and liver damage, as measured by quantitative polymerase chain reaction and
histology activity index, were related to genotype and core promoter mutations in 43 chronic …
histology activity index, were related to genotype and core promoter mutations in 43 chronic …