Statins are a class of drugs used to lower low-density lipoprotein cholesterol and are
amongst the most prescribed medications worldwide. Most statins work as a competitive …

Satins are the most frequently prescribed and efficient drugs for treatment of lipid disorders.
These drugs represent one of the most valuable therapeutic classes of compounds in the …

This study aimed to comprehensively investigate the in vitro metabolism of statins. The
metabolism of clinically relevant concentrations of atorvastatin, fluvastatin, pitavastatin …

Hyperlipidemia influences on numerous diseases, such as atherosclerosis, hypertension,
and diabetes mellitus, however it still treatable. Atorvastatin is one of the most common …

Statins are lipid-lowering drugs used widely to prevent and treat cardiovascular and
coronary heart diseases. These drugs are among the most commonly prescribed medicines …

Atorvastatin (ATV) inhibits the HMG-CoA reductase. This compound is believed to exhibit
high radical scavenging abilities against lipoprotein oxidation, warranting an investigation of …

The pharmaceutical success of atorvastatin (ATV), a widely employed drug against the “bad”
cholesterol (LDL) and cardiovascular diseases, traces back to its ability to scavenge free …

Abbreviations: drug-drug interactions (DDI), human serum albumin (HSA), area under the
curve fold ratio (AUCR), free energy change (ΔG), electron affinity (EA), reactive oxygen …

The esterification of levulinic acid (LA) to alkyl levulinate esters from biomass by
heterogeneous acid catalysis is a potential chemical route for the sustainable production of …

Aims The aim of this study is to determine the pharmacokinetic parameters of atorvastatin
calcium (AT) and ezetimibe (EZ) in human volunteers following the administration of a single …