In response to vessel injury (or other pathological conditions), the hemostatic process is
activated, resulting in a fibrous, cellular-rich structure commonly referred to as a blood clot …

Gender-affirming hormonal therapies are a critical component of the care of transgender
individuals. Transgender people are commonly prescribed estrogen or testosterone to …

Haemorrhagic shock is frequent in critical care settings and responsible for a high mortality
rate due to multiple organ dysfunction and coagulopathy. The management of critically ill …

Fibrinolysis is initiated by the activation of plasminogen to plasmin via tissue-plasminogen
activator (tPA) and urokinase-plasminogen activator (uPA); plasmin then converts fibrin to …

Hematological abnormalities are common in cirrhosis and are associated with various
pathophysiological mechanisms. Studies have documented a prevalence of …

Background Cancer and atrial fibrillation (AF) are common concurrent disorders. Direct oral
anticoagulants (DOACs) are prescribed to prevent stroke in patients with AF. Patients with …

Viscoelastic testing is a clinically available method to assess hypercoagulability. This
systematic review aims to provide a comprehensive overview of the existing literature and …

Background: Viscoelastic hemostatic assays (VHAs) have become an integral diagnostic
tool in guiding hemostatic therapy, offering new opportunities in personalized hemostatic …

Synthetic corticosteroids are widely used due to their anti-inflammatory and
immunosuppressant effects. Their use has been associated with venous thromboembolism …

Arterial and venous thromboembolism are leading causes of morbidity and death worldwide.
Despite significant advances in the diagnosis, prognostication, and treatment of thrombotic …