Redox reactions are intrinsically linked to energy metabolism. Therefore, redox processes
are indispensable for organismal physiology and life itself. The term reactive oxygen species …

Breast cancer is the most frequently occurring cancer in women. Chemotherapy in
combination with immunotherapy has been used to treat breast cancer. Atezolizumab …

Post-translational changes in the redox state of cysteine residues can rapidly and reversibly
alter protein functions, thereby modulating biological processes. The nematode C. elegans …

Auranofin (AUR) is an orally available lipophilic gold-based anti-inflammatory compound
used for the treatment of rheumatoid arthritis (RA). Recent evidence indicates that AUR may …

Skeletal muscle insulin resistance is the earliest defect in type 2 diabetes (T2D), preceding
and predicting disease development. To what extent this reflects a primary defect or is …

Autophagy is a ubiquitous homeostatic mechanism for the degradation or turnover of cellular
components. Degradation of mitochondria via autophagy (mitophagy) is involved in a …

Abstract 'Turn-on'fluorescence probes for detecting H2O2 in cells are established, but
equivalent tools to monitor the products of its reaction with protein cysteines have not been …

The peptide hormone insulin is a key regulator of energy metabolism, proliferation and
survival. Binding of insulin to its receptor activates the PI3K/AKT signalling pathway, which …

One of the hallmark features in the neurodegenerative disorders (NDDs) is the accumulation
of aggregated and/or non-functional protein in the cellular milieu. Post-translational …

Reduction and oxidation reactions are essential for biochemical processes. They are part of
metabolic pathways and signal transduction. Reactive oxygen species (ROS) as second …