Recurrent topics in mass spectrometry-based metabolomics and lipidomics—standardization, coverage, and throughput
We have come a long way in the last years of developing analytical strategies in
metabolomics. We have seen huge progress in tackling multiplatform measurement, data …
metabolomics. We have seen huge progress in tackling multiplatform measurement, data …
[HTML][HTML] Ceramides and ceramide synthases in cancer: Focus on apoptosis and autophagy
J Alizadeh, SC da Silva Rosa, X Weng, J Jacobs… - European Journal of …, 2023 - Elsevier
Different studies corroborate a role for ceramide synthases and their downstream products,
ceramides, in modulation of apoptosis and autophagy in the context of cancer. These …
ceramides, in modulation of apoptosis and autophagy in the context of cancer. These …
Lipidomic profiling of human serum enables detection of pancreatic cancer
D Wolrab, R Jirásko, E Cífková, M Höring, D Mei… - Nature …, 2022 - nature.com
Pancreatic cancer has the worst prognosis among all cancers. Cancer screening of body
fluids may improve the survival time prognosis of patients, who are often diagnosed too late …
fluids may improve the survival time prognosis of patients, who are often diagnosed too late …
A super-resolution strategy for mass spectrometry imaging via transfer learning
High-spatial-resolution mass spectrometry imaging (HSR-MSI) provides precise spatial
information on thousands of biomolecules without labelling across a tissue section. Deep …
information on thousands of biomolecules without labelling across a tissue section. Deep …
Validation of lipidomic analysis of human plasma and serum by supercritical fluid chromatography–mass spectrometry and hydrophilic interaction liquid …
D Wolrab, M Chocholoušková, R Jirásko… - Analytical and …, 2020 - Springer
Ultrahigh-performance supercritical fluid chromatography–mass spectrometry
(UHPSFC/MS) has a great potential for the high-throughput lipidomic quantitation of …
(UHPSFC/MS) has a great potential for the high-throughput lipidomic quantitation of …
Reprogrammed lipid metabolism and the lipid-associated hallmarks of colorectal cancer
Simple Summary Colorectal cancer (CRC) is the third-most diagnosed cancer and the
second-leading cause of cancer-related deaths worldwide. Limitations in early and accurate …
second-leading cause of cancer-related deaths worldwide. Limitations in early and accurate …
Ultrahigh-performance supercritical fluid chromatography/mass spectrometry in the lipidomic analysis
D Wolrab, O Peterka, M Chocholoušková… - TrAC Trends in …, 2022 - Elsevier
Ultrahigh-performance supercritical fluid chromatography/mass spectrometry (UHPSFC/MS)
is one of the fastest analytical approaches for high-throughput lipidomic analysis covering a …
is one of the fastest analytical approaches for high-throughput lipidomic analysis covering a …
Plasma lipidomic profiles of kidney, breast and prostate cancer patients differ from healthy controls
D Wolrab, R Jirásko, O Peterka, J Idkowiak… - Scientific Reports, 2021 - nature.com
Early detection of cancer is one of the unmet needs in clinical medicine. Peripheral blood
analysis is a preferred method for efficient population screening, because blood collection is …
analysis is a preferred method for efficient population screening, because blood collection is …
Lipidomic characterization of exosomes isolated from human plasma using various mass spectrometry techniques
O Peterka, R Jirásko, M Chocholoušková… - … et Biophysica Acta (BBA …, 2020 - Elsevier
Ultrahigh-performance supercritical fluid chromatography-mass spectrometry
(UHPSFC/MS), ultrahigh-performance liquid chromatography-mass spectrometry …
(UHPSFC/MS), ultrahigh-performance liquid chromatography-mass spectrometry …
Retention dependences support highly confident identification of lipid species in human plasma by reversed-phase UHPLC/MS
Z Vaňková, O Peterka, M Chocholoušková… - Analytical and …, 2022 - Springer
Reversed-phase ultrahigh-performance liquid chromatography-mass spectrometry (RP-
UHPLC/MS) method was developed with the aim to unambiguously identify a large number …
UHPLC/MS) method was developed with the aim to unambiguously identify a large number …