Abstract Development of the pharmacology of Acid-Sensing Ion Channels (ASICs) has
become a key challenge to study their structure, their molecular and cellular functions and …

Acid‐sensing ion channels (ASICs) are a family of proton‐sensing channels that are voltage
insensitive, cation selective (mostly permeable to Na+), and nonspecifically blocked by …

Acid Sensing Ion Channels (ASIC) are proton sensors involved in several physiological and
pathophysiological functions including synaptic plasticity, sensory systems and nociception …

Dysregulation in glutamatergic receptors and transporters has been found to mediate drugs
of abuse, including morphine. Among glutamate receptors, ionotropic glutamate receptors …

Biological invasions are a threat to global biodiversity and provide unique opportunities to
study ecological processes. Population bottlenecks are a common feature of biological …

This study aimed to explore the role of acid-sensing ion channel 3 (ASIC3) in the modulation
of tooth mechanical hyperalgesia induced by orthodontic tooth movement. In male Sprague …

The present study was conducted to evaluate the analgesic potential of the new triamilide
macrolide antibiotic, tulathromycin, at 20 and 40 mg/kg of body weight (BW), subcutaneously …

Abstract GMQ (2-guanidine-4-methylquinazoline or N-(4-methyl-2-quinazolinyl)-guanidine
hydrochloride), an agonist of acid-sensing ion channel type 3, has been increasingly used …

Objectives To assess the antinociceptive activity of the neomycin derivatives neamine and 2-
deoxystreptamine following intraspinal administration in rats. Methods We used the tail-flick …

Improved sanitary conditions, disease prevention (eg, vaccinations) and treatment (eg,
antibiotics) have increased life expectancy, up to the 67.2 years value in 2010 …