Maternal and paternal factors influence offspring development and program its genome for
successful postnatal life. Based on the stressors during gestation, the pregnant female …

Gene–environment interactions begin at conception to influence maternal/placental/fetal
triads, neonates, and children with short-and long-term effects on brain development. Life …

Mucosal immunity develops in the human fetal intestine by 11–14 weeks of gestation, yet
whether viable microbes exist in utero and interact with the intestinal immune system is …

Background Endothelial cell (EC) injury accelerates the progression of diabetic
macrovascular complications. Hypoxia is an important cause of EC injury. Hypoxia-inducible …

Maternal asthma status, prenatal exposures, and infant gut microbiota perturbation are
associated with heightened risk of atopy and asthma risk in childhood, observations …

Hypoxia is a common and severe stress to an organism's homeostatic mechanisms, and
hypoxia during gestation is associated with significantly increased incidence of maternal …

Intrauterine growth restriction (IUGR) is associated with reduced kidney size at birth,
accelerated renal function decline, and increased risk for chronic kidney and cardiovascular …

Perinatal asphyxia (PA) is a burdening pathology with high short-term mortality and severe
long-term consequences. Its incidence, reaching as high as 10 cases per 1000 live births in …

Though the pathophysiology of schizophrenia remains poorly understood, altered brain
energy metabolism is increasingly implicated. Here, we conduct meta-analyses of the …

Maternal hypoxia, characterized by insufficient oxygen supply during pregnancy, poses
significant risks to both maternal and fetal health, particularly through its impact on placental …