Regulation of mRNA decay in bacteria
BK Mohanty, SR Kushner - Annual Review of Microbiology, 2016 - annualreviews.org
Gram-negative and gram-positive bacteria use a variety of enzymatic pathways to degrade
mRNAs. Although several recent reviews have outlined these pathways, much less attention …
mRNAs. Although several recent reviews have outlined these pathways, much less attention …
Methodologies for bacterial ribonuclease characterization using RNA-seq
Bacteria adjust gene expression at the post-transcriptional level through an intricate network
of small regulatory RNAs and RNA-binding proteins, including ribonucleases (RNases) …
of small regulatory RNAs and RNA-binding proteins, including ribonucleases (RNases) …
The stability of an mRNA is influenced by its concentration: a potential physical mechanism to regulate gene expression
S Nouaille, S Mondeil, AL Finoux, C Moulis… - Nucleic acids …, 2017 - academic.oup.com
Changing mRNA stability is a major post-transcriptional way of controlling gene expression,
particularly in newly encountered conditions. As the concentration of mRNA is the result of …
particularly in newly encountered conditions. As the concentration of mRNA is the result of …
Proteomic and transcriptomic experiments reveal an essential role of RNA degradosome complexes in shaping the transcriptome of Mycobacterium tuberculosis
P Płociński, M Macios, J Houghton… - Nucleic acids …, 2019 - academic.oup.com
The phenotypic adjustments of Mycobacterium tuberculosis are commonly inferred from the
analysis of transcript abundance. While mechanisms of transcriptional regulation have been …
analysis of transcript abundance. While mechanisms of transcriptional regulation have been …
A cooperative PNPase-Hfq-RNA carrier complex facilitates bacterial riboregulation
Polynucleotide phosphorylase (PNPase) is an ancient exoribonuclease conserved in the
course of evolution and is found in species as diverse as bacteria and humans …
course of evolution and is found in species as diverse as bacteria and humans …
Enzymes involved in posttranscriptional RNA metabolism in gram‐negative bacteria
BK Mohanty, SR Kushner - … with RNA in Bacteria and Archaea, 2018 - Wiley Online Library
All living organisms, including the Gram‐negative bacteria, have two major classes of RNA
molecules. mRNAs contain the information for the synthesis of the various proteins that are …
molecules. mRNAs contain the information for the synthesis of the various proteins that are …
RNase E and the high-fidelity orchestration of RNA metabolism
KJ Bandyra, BF Luisi - Microbiology spectrum, 2018 - Am Soc Microbiol
The bacterial endoribonuclease RNase E occupies a pivotal position in the control of gene
expression, as its actions either commit transcripts to an irreversible fate of rapid destruction …
expression, as its actions either commit transcripts to an irreversible fate of rapid destruction …
Architectural principles for Hfq/Crc-mediated regulation of gene expression
XY Pei, T Dendooven, E Sonnleitner, S Chen, U Bläsi… - elife, 2019 - elifesciences.org
In diverse bacterial species, the global regulator Hfq contributes to post-transcriptional
networks that control expression of numerous genes. Hfq of the opportunistic pathogen …
networks that control expression of numerous genes. Hfq of the opportunistic pathogen …
Polynucleotide phosphorylase: Not merely an RNase but a pivotal post-transcriptional regulator
Almost 60 years ago, Severo Ochoa was awarded the Nobel Prize in Physiology or
Medicine for his discovery of the enzymatic synthesis of RNA by polynucleotide …
Medicine for his discovery of the enzymatic synthesis of RNA by polynucleotide …
The conserved 3′ UTR-derived small RNA NarS mediates mRNA crossregulation during nitrate respiration
Small noncoding RNAs (sRNAs) from mRNA 3′ UTRs seem to present a previously
unrecognized layer of bacterial post-transcriptional control whereby mRNAs influence each …
unrecognized layer of bacterial post-transcriptional control whereby mRNAs influence each …