[HTML][HTML] Maternal immune protection against infectious diseases
The maternal immune system protects developing offspring against pathogens before birth
via transplacental transfer and after birth through secreted milk. This transferred maternal …
via transplacental transfer and after birth through secreted milk. This transferred maternal …
[HTML][HTML] NK cells in HIV-1 infection: from basic science to vaccine strategies
NK cells play a key role in immune response against HIV infection. These cells can destroy
infected cells and contribute to adequate and strong adaptive immune responses, by acting …
infected cells and contribute to adequate and strong adaptive immune responses, by acting …
[HTML][HTML] Polyfunctional HIV-specific antibody responses are associated with spontaneous HIV control
ME Ackerman, A Mikhailova, EP Brown… - PLoS …, 2016 - journals.plos.org
Elite controllers (ECs) represent a unique model of a functional cure for HIV-1 infection as
these individuals develop HIV-specific immunity able to persistently suppress viremia …
these individuals develop HIV-specific immunity able to persistently suppress viremia …
[HTML][HTML] Elimination of HIV-1-infected cells by broadly neutralizing antibodies
T Bruel, F Guivel-Benhassine, S Amraoui… - Nature …, 2016 - nature.com
The Fc region of HIV-1 Env-specific broadly neutralizing antibodies (bNAbs) is required for
suppressing viraemia, through mechanisms which remain poorly understood. Here, we …
suppressing viraemia, through mechanisms which remain poorly understood. Here, we …
Comparison of antibody-dependent cell-mediated cytotoxicity and virus neutralization by HIV-1 Env-specific monoclonal antibodies
B von Bredow, JF Arias, LN Heyer, B Moldt… - Journal of …, 2016 - Am Soc Microbiol
Although antibodies to the human immunodeficiency virus type 1 (HIV-1) envelope
glycoprotein have been studied extensively for their ability to block viral infectivity, little data …
glycoprotein have been studied extensively for their ability to block viral infectivity, little data …
Antibody-dependent cellular cytotoxicity in HIV infection
DN Forthal, A Finzi - Aids, 2018 - journals.lww.com
Interactions between the Fc segment of IgG and its receptors (FcγRs) found on cells such as
natural killer cells, monocytes, macrophages and neutrophils can potentially mediate …
natural killer cells, monocytes, macrophages and neutrophils can potentially mediate …
[HTML][HTML] Understanding protection from SARS-CoV-2 by studying reinfection
J Overbaugh - Nature Medicine, 2020 - nature.com
Understanding protection from SARS-CoV-2 by studying reinfection | Nature Medicine Skip to
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main content Thank you for visiting nature.com. You are using a browser version with limited …
Vesicular antibodies: a bioactive multifunctional combination platform for targeted therapeutic delivery and cancer immunotherapy
The ability to selectively kill cancerous cell populations while leaving healthy cells
unaffected is a key goal in oncology. The use of nanovesicles (NVs) as chemotherapeutic …
unaffected is a key goal in oncology. The use of nanovesicles (NVs) as chemotherapeutic …
Ebola vaccine–induced protection in nonhuman primates correlates with antibody specificity and Fc-mediated effects
Although substantial progress has been made with Ebola virus (EBOV) vaccine measures,
the immune correlates of vaccine-mediated protection remain uncertain. Here, five mucosal …
the immune correlates of vaccine-mediated protection remain uncertain. Here, five mucosal …
[HTML][HTML] Mind the gap: how interspecies variability in IgG and its receptors may complicate comparisons of human and non-human primate effector function
AR Crowley, ME Ackerman - Frontiers in immunology, 2019 - frontiersin.org
The field of HIV research relies heavily on non-human primates, particularly the members of
the macaque genus, as models for the evaluation of candidate vaccines and monoclonal …
the macaque genus, as models for the evaluation of candidate vaccines and monoclonal …