Human cytomegalovirus (HCMV) is a herpesvirus that infects~ 60% of adults in developed
countries and more than 90% in developing countries. Usually, it is controlled by a vigorous …

Pregnancy is a unique type of immunological process. Healthy pregnancy is associated with
a series of inflammatory events: implantation (inflammation), gestation (anti-inflammation) …

Cytomegalovirus is the most common congenital infection, affecting 0.5–2% of all live births
and the main nongenetic cause of congenital sensorineural hearing loss and neurological …

Some maternal infections, contracted before or during pregnancy, can be transmitted to the
fetus, during gestation (congenital infection), during labor and childbirth (perinatal infection) …

Cytomegalovirus establishes a lifelong latent infection following primary infection that can
periodically reactivate with shedding of infectious virus. Primary infection, reactivation and …

Pro-inflammatory cytokines of a T helper-1-signature are known to promote insulin
resistance (IR) in obesity, but the physiological role of this mechanism is unclear. It is also …

Why certain viruses cross the physical barrier of the human placenta but others do not is
incompletely understood. Over the past 20 years, we have gained deeper knowledge of …

Background Studies have suggested that CMV infection may influence cardiovascular
disease (CVD) risk and mortality. However, there have been no large-scale examinations of …

The hallmark of human early pregnancy is the accumulation of a unique population of
Natural Killer (dNK) cells at the main maternal-fetal interface, the decidua basalis. dNK cells …

Congenital cytomegalovirus (CMV) infection is a leading cause of developmental
disabilities. In the United States during the period 1988–1994, approximately one-quarter of …