Sepsis-associated acute kidney injury (SA-AKI) is common in critically ill patients and is
strongly associated with adverse outcomes, including an increased risk of chronic kidney …

Acute respiratory distress syndrome (ARDS) is characterised by acute hypoxaemic
respiratory failure with bilateral infiltrates on chest imaging, which is not fully explained by …

Sepsis arises from diverse and incompletely understood dysregulated host response
processes following infection that leads to life-threatening organ dysfunction. Here we …

Background In sepsis and acute respiratory distress syndrome (ARDS), heterogeneity has
contributed to difficulty identifying effective pharmacotherapies. In ARDS, two molecular …

Purpose Sepsis is a heterogeneous syndrome and identification of sub-phenotypes is
essential. This study used trajectories of vital signs to develop and validate sub-phenotypes …

The premier single-volume reference in the field of anesthesia, Clinical Anesthesia is now in
its Sixth Edition, with thoroughly updated coverage, a new full-color design, and a revamped …

Purpose The heterogeneity in sepsis is held responsible, in part, for the lack of precision
treatment. Many attempts to identify subtypes of sepsis patients identify those with shared …

Sepsis, defined as life-threatening organ dysfunction caused by a dysregulated host
response to an infection, remains a major challenge for clinicians and trialists. Despite …

Background Severe weakness associated with critical illness (CIW) is common. This
narrative review summarizes the latest scientific insights and proposes a guide for clinicians …

Acute kidney injury (AKI) is a prototypical example of a common syndrome in critical illness
defined by consensus. The consensus definition for AKI, traditionally defined using only …