Gut microbiome lipid metabolism and its impact on host physiology
Metabolites produced by commensal gut microbes impact host health through their
recognition by the immune system and their influence on numerous metabolic pathways …
recognition by the immune system and their influence on numerous metabolic pathways …
Human metabolome variation along the upper intestinal tract
Most processing of the human diet occurs in the small intestine. Metabolites in the small
intestine originate from host secretions, plus the ingested exposome and microbial …
intestine originate from host secretions, plus the ingested exposome and microbial …
Membrane lipids from gut microbiome-associated bacteria as structural and signalling molecules
Bacteria produce an array of diverse, dynamic and often complex lipid structures, some of
which function beyond their typical role in membrane structure. The model organism, E. coli …
which function beyond their typical role in membrane structure. The model organism, E. coli …
Role and interaction of bacterial sphingolipids in human health
Sphingolipids, present in both higher animals and prokaryotes, involving in cell
differentiation, pathogenesis and apoptosis in human physiological health. With increasing …
differentiation, pathogenesis and apoptosis in human physiological health. With increasing …
Arsinothricin Biosynthesis Involving a Radical SAM Enzyme for Noncanonical SAM Cleavage and C–As Bond Formation
Y Yao, J He, F Chen, M Dong - Journal of the American Chemical …, 2024 - ACS Publications
Arsinothricin is a potent antibiotic secreted by soil bacteria. The biosynthesis of arsinothricin
was proposed to involve a C–As bond formation between trivalent As and the 3-amino-3 …
was proposed to involve a C–As bond formation between trivalent As and the 3-amino-3 …
Structure revision of a widespread marine sulfonolipid class based on isolation and total synthesis
D Roman, P Meisinger, R Guillonneau… - Angewandte Chemie …, 2024 - Wiley Online Library
The cosmopolitan marine Roseobacter clade is of global biogeochemical importance.
Members of this clade produce sulfur‐containing amino lipids (SALs) involved in biofilm …
Members of this clade produce sulfur‐containing amino lipids (SALs) involved in biofilm …
Biosynthetic enzyme analysis identifies a protective role for TLR4-acting gut microbial sulfonolipids in inflammatory bowel disease
The trillions of microorganisms inhabiting the human gut are intricately linked to human
health. While specific microbes have been associated with diseases, microbial abundance …
health. While specific microbes have been associated with diseases, microbial abundance …
[HTML][HTML] A neonatal piglet model reveals interactions between nasal microbiota and influenza A virus pathogenesis
While vaccination and therapeutics for prevention/treatment of influenza are available, new
strategies are needed to combat influenza disease in susceptible populations, particularly …
strategies are needed to combat influenza disease in susceptible populations, particularly …
Biochemical characterization of the first step in sulfonolipid biosynthesis in Alistipes finegoldii
CD Radka, DJ Miller, MW Frank, CO Rock - Journal of Biological Chemistry, 2022 - ASBMB
Sulfonolipids are unusual lipids found in the outer membranes of Gram-negative bacteria in
the phylum Bacteroidetes. Sulfonolipid and its deacylated derivative, capnine, are sulfur …
the phylum Bacteroidetes. Sulfonolipid and its deacylated derivative, capnine, are sulfur …
Vegetable phylloplane microbiomes harbour class 1 integrons in novel bacterial hosts and drive the spread of chlorite resistance
Bacterial hosts in vegetable phylloplanes carry mobile genetic elements, such as plasmids
and transposons that are associated with integrons. These mobile genetic elements and …
and transposons that are associated with integrons. These mobile genetic elements and …