Successful pregnancy requires carefully-coordinated communications between the mother
and fetus. Immune cells and cytokine signaling pathways participate as mediators of these …

The comparison of the immunological state of pregnancy to an immunosuppressed host–
graft model continues to lead research and clinical practice to ill-defined approaches. This …

Although much progress is being made in understanding the molecular pathways in the
placenta that are involved in the pathophysiology of pregnancy-related disorders, a …

Intrauterine infection and inflammation are known risk factors for brain damage in the
neonate irrespective of the gestational age. Infection‐induced maternal immune activation …

Exposure to prenatal inflammation is a known risk factor for long term neurobehavioral
disorders including cerebral palsy, schizophrenia, and autism. Models of systemic …

Problem The diagnosis of microbial invasion of the amniotic cavity (MIAC) has been
traditionally performed using traditional cultivation techniques, which require growth of …

Several different bodies of evidence support a link between infection and altered brain
development. Maternal infections, such as influenza and human immunodeficiency virus …

Pregnancy is a unique condition where the maternal immune system is continuously
adapting in response to the stages of fetal development and signals from the environment …

Dysbiosis of the gut microbiome in preterm infants predisposes the neonate to various major
morbidities including neonatal necrotizing enterocolitis and sepsis in the neonatal intensive …

Children of obese mothers are at increased risk of developmental adversities. Maternal
obesity is linked to an inflammatory in utero environment, which, in turn, is associated with …