Simple Summary The relationship between the immune system and tumours is currently one
of the most studied topics in the field of cancer. Previously, it was thought that a tumour could …

Human basophils, first identified over 140 years ago, account for just 0.5-1% of circulating
leukocytes. While this scarcity long hampered basophil studies, innovations during the past …

Type 2 cytokine responses promote parasitic immunity and initiate tissue repair; however,
they can also result in immunopathologies when not properly restricted. Although basophilia …

Basophils were identified in human peripheral blood by Paul Ehrlich over 140 years ago.
Human basophils represent< 1% of peripheral blood leukocytes. During the last decades …

Helminths, including nematodes, cestodes and trematodes, are complex parasitic organisms
that infect at least one billion people globally living in extreme poverty. Helminthic infections …

Parasitic helminth infections remain a significant global health issue and are responsible for
devastating morbidity and economic hardships. During infection, helminths migrate through …

The β common chain (βc) cytokine family includes granulocyte-macrophage colony-
stimulating factor (GM-CSF), interleukin-3 (IL-3) and IL-5, all of which use βc as key …

Helminths remain one of the most prolific pathogens in the world. Following infection
helminths interact with various epithelial cell surfaces, including skin, lung, and gut. Recent …

The transcription factor MYB is a crucial regulator of hematopoietic stem and progenitor
cells. However, the nature of lineage-specific enhancer usage of the Myb gene is largely …

Basophils represent approximately 1% of human peripheral blood leukocytes. Their effector
functions were initially appreciated in the 1970s when basophils were shown to express the …