Mitochondria play a pivotal role in bioenergetics and respiratory functions, which are
essential for the numerous biochemical processes underpinning cell viability. Mitochondrial …

Executive summary Acting now on dementia prevention, intervention, and care will vastly
improve living and dying for individuals with dementia and their families, and in doing so …

Background Alzheimer's disease (AD), as the most common cause of dementia, brings huge
economic burden for patients and social health care systems, which motivates researchers …

Increasing evidence suggests that Alzheimer's disease pathogenesis is not restricted to the
neuronal compartment, but includes strong interactions with immunological mechanisms in …

Background: Alzheimer's disease (AD) and dementia are chronic diseases with progressive
deterioration of cognition, function, and behavior leading to severe disability and death. The …

Alzheimer's disease (AD) is a chronic neurodegenerative disease, with the characteristics of
neurofibrillary tangle (NFT) and senile plaque (SP) formation. Although great progresses …

Physical activity provides clinical benefit in Parkinson's disease (PD). Irisin is an exercise-
induced polypeptide secreted by skeletal muscle that crosses the blood–brain barrier and …

Increasing evidence indicates that reactive oxygen species (ROS), consisting of superoxide,
hydrogen peroxide, and multiple others, do not only cause oxidative stress, but rather may …

In this review, we explore the association among physical activity, cardiorespiratory fitness,
and exercise on gray matter volume in older adults. We conclude that higher …

Prior research has found that cognitive benefits of physical exercise and brain health in
older adults may be enhanced when mental exercise is interactive simultaneously, as in …