Currently, more than 170 modifications have been identified on RNA. Among these RNA
modifications, various methylations account for two-thirds of total cases and exist on almost …

Transfer RNAs (tRNAs) play pivotal roles in the transmission of genetic information, and
abnormality of tRNAs directly leads to translation disorders and causes diseases, including …

Gliomas are highly malignant tumors accounting for the majority of brain neoplasms. They
are characterized by nuclear atypia, high mitotic rate and cellular polymorphism that often …

Background: The pseudouridine synthases (PUSs) have been reported to be associated
with cancers. However, their involvement in hepatocellular carcinoma (HCC) has not been …

Diabetes mellitus (DM) and its related complications are among the leading causes of
disability and mortality worldwide. Substantial studies have explored epigenetic regulation …

Background RNA pseudouridylation is a critical post‐transcriptional modification that
influences gene expression and impacts various biological functions. Despite its …

Abstract tRNA is one of the most conserved and abundant RNA species, which plays a key
role during protein translation. tRNA molecules are post-transcriptionally modified by tRNA …

Abstract Pseudouridine synthase 7 (PUS7) may play key roles in cancer development.
However, few studies have been conducted in this area. In the present study, we explored …

RNA methylation is widespread in nature. Abnormal expression of proteins associated with
RNA methylation is strongly associated with a number of human diseases including cancer …

Alzheimer's disease (AD) is a complex neurodegenerative disorder and the most common
form of dementia. There are two main types of AD: familial and sporadic. Familial AD is …