Principles in the design of ligand-targeted cancer therapeutics and imaging agents
M Srinivasarao, CV Galliford, PS Low - Nature reviews Drug discovery, 2015 - nature.com
Most cancer drugs are designed to interfere with one or more events in cell proliferation or
survival. As healthy cells may also need to proliferate and avoid apoptosis, anticancer …
survival. As healthy cells may also need to proliferate and avoid apoptosis, anticancer …
PSMA-targeted radiopharmaceuticals for imaging and therapy
HJ Wester, M Schottelius - Seminars in nuclear medicine, 2019 - Elsevier
As described in more detail in other contributions in this issue of Seminars in Nuclear
Medicine, prostate-specific membrane antigen (PSMA) has become one of the most …
Medicine, prostate-specific membrane antigen (PSMA) has become one of the most …
The theranostic PSMA ligand PSMA-617 in the diagnosis of prostate cancer by PET/CT: biodistribution in humans, radiation dosimetry, and first evaluation of tumor …
A Afshar-Oromieh, H Hetzheim… - Journal of Nuclear …, 2015 - Soc Nuclear Med
PET imaging with the prostate-specific membrane antigen (PSMA)–targeted radioligand
68Ga-PSMA-11 is regarded as a significant step forward in the diagnosis of prostate cancer …
68Ga-PSMA-11 is regarded as a significant step forward in the diagnosis of prostate cancer …
Preclinical evaluation and first patient application of 99mTc-PSMA-I&S for SPECT imaging and radioguided surgery in prostate cancer
S Robu, M Schottelius, M Eiber, T Maurer… - Journal of Nuclear …, 2017 - Soc Nuclear Med
Initial studies in patients have demonstrated the suitability of 111In-PSMA-I&T (111In-
DOTAGA-(3-iodo-y)-fk-Sub (KuE))(PSMA is prostate-specific membrane antigen and I&T is …
DOTAGA-(3-iodo-y)-fk-Sub (KuE))(PSMA is prostate-specific membrane antigen and I&T is …
New strategies in prostate cancer: prostate-specific membrane antigen (PSMA) ligands for diagnosis and therapy
Key issues for prostate cancer patients are the detection of recurrent disease and the
treatment of metastasized cancer. Early detection is a major challenge for all conventional …
treatment of metastasized cancer. Early detection is a major challenge for all conventional …
Targeting prostate cancer: prostate‐specific membrane antigen based diagnosis and therapy
T Wüstemann, U Haberkorn, J Babich… - Medicinal research …, 2019 - Wiley Online Library
The high incidence rates of prostate cancer (PCa) raise demand for improved therapeutic
strategies. Prostate tumors specifically express the prostate‐specific membrane antigen …
strategies. Prostate tumors specifically express the prostate‐specific membrane antigen …
Technetium‐99m radiochemistry for pharmaceutical applications
D Papagiannopoulou - Journal of Labelled Compounds and …, 2017 - Wiley Online Library
Technetium‐99m (99mTc) is a widely used radionuclide, and the development of 99mTc
imaging agents continues to be in demand. This overview discusses basic principles of …
imaging agents continues to be in demand. This overview discusses basic principles of …
[HTML][HTML] Prostate-specific membrane antigen as a target for cancer imaging and therapy
The prostate-specific membrane antigen (PSMA) is a molecular target whose use has
resulted in some of the most productive work toward imaging and treating prostate cancer …
resulted in some of the most productive work toward imaging and treating prostate cancer …
[HTML][HTML] Advances in PSMA theranostics
TM Jeitner, JW Babich, JM Kelly - Translational Oncology, 2022 - Elsevier
The validation of prostate specific membrane antigen (PSMA) as a molecular target in
metastatic castration-resistant prostate cancer has stimulated the development of multiple …
metastatic castration-resistant prostate cancer has stimulated the development of multiple …
[HTML][HTML] The future of PSMA-targeted radionuclide therapy: an overview of recent preclinical research
EAM Ruigrok, WM van Weerden, J Nonnekens… - Pharmaceutics, 2019 - mdpi.com
Prostate specific membrane antigen (PSMA) has become a major focus point in the research
and development of prostate cancer (PCa) imaging and therapeutic strategies using …
and development of prostate cancer (PCa) imaging and therapeutic strategies using …