By permitting direct visualization of the airspaces of the lung, magnetic resonance imaging
(MRI) using hyperpolarized gases provides unique strategies for evaluating pulmonary …

This article reviews the physics and technology of producing large quantities of highly spin-
polarized He 3 nuclei using spin-exchange (SEOP) and metastability-exchange (MEOP) …

Conventional pulmonary function tests appear normal in early cystic fibrosis (CF) lung
disease. Therefore, new diagnostic approaches are required that can detect CF lung …

Purpose The goal of this work was to investigate lung morphological changes associated
with chronic obstructive pulmonary disease (COPD) using hyperpolarized 129Xe diffusion …

A new noninvasive, nonradioactive approach for glucose imaging using spin
hyperpolarization technology and stable isotope labeling is presented. A glucose analog …

Purpose Inert fluorinated gas lung MRI is a new and promising alternative to hyperpolarized
gas lung MRI; it is less expensive and does not require expensive isotopes/polarizers. The …

Purpose: Radiation induced lung injury (RILI) is a common side effect for patients
undergoing thoracic radiation therapy (RT). RILI can lead to temporary or permanent loss of …

Purpose To develop and optimize a rapid dynamic hyperpolarized 129Xe ventilation (DXeV)
MRI protocol and investigate the feasibility of capturing pulmonary signal‐time curves in …

Purpose To implement and optimize a single‐shot spiral encoding strategy for rapid 2D
IDEAL projection imaging of hyperpolarized (Hp) 129Xe in the gas phase, and in the …

Hyperpolarized 129 Xe magnetic resonance imaging is a powerful modality capable of
assessing lung structure and function. While it has shown promise as a clinical tool for the …