Recent advances and new strategies in Leishmaniasis diagnosis
RCF De Brito, RDO Aguiar-Soares… - Applied Microbiology …, 2020 - Springer
Leishmaniasis is a set of complex and multifaceted syndromes, with different clinical
manifestations, caused by different species of the genus Leishmania spp. that can be …
manifestations, caused by different species of the genus Leishmania spp. that can be …
Leishmania Vesicle-Depleted Exoproteome: What, Why, and How?
S Esteves, I Costa, S Luelmo, N Santarém… - Microorganisms, 2022 - mdpi.com
Leishmaniasis, a vector-borne parasitic protozoan disease, is among the most important
neglected tropical diseases. In the absence of vaccines, disease management is …
neglected tropical diseases. In the absence of vaccines, disease management is …
Understanding Leishmania parasites through proteomics and implications for the clinic
S Sundar, B Singh - Expert review of proteomics, 2018 - Taylor & Francis
Introduction: Leishmania spp. are causative agents of leishmaniasis, a broad-spectrum
neglected vector-borne disease. Genomic and transcriptional studies are not capable of …
neglected vector-borne disease. Genomic and transcriptional studies are not capable of …
Label-Free Mass Spectrometry Proteomics Reveals Different Pathways Modulated in THP-1 Cells Infected with Therapeutic Failure and Drug Resistance Leishmania …
L Tagliazucchi, A Perea-Martinez, G Fiorini… - ACS Infectious …, 2023 - ACS Publications
As the world is facing increasing difficulties to treat leishmaniasis with current therapies,
deeper investigation into the molecular mechanisms responsible for both drug resistance …
deeper investigation into the molecular mechanisms responsible for both drug resistance …
Intramuscular Immunization with a Liposomal Multi-Epitope Chimeric Protein Induces Strong Cellular Immune Responses against Visceral Leishmaniasis
M Agallou, M Margaroni, E Karagouni - Vaccines, 2023 - mdpi.com
Control of the intracellular parasite Leishmania (L.) requires the activation of strong type 1
cellular immune responses. Towards this goal, in the present study, a multiepitope chimeric …
cellular immune responses. Towards this goal, in the present study, a multiepitope chimeric …
The Experimental Proteome of Leishmania infantum Promastigote and Its Usefulness for Improving Gene Annotations
Á Sanchiz, E Morato, A Rastrojo, E Camacho… - Genes, 2020 - mdpi.com
Leishmania infantum causes visceral leishmaniasis (kala-azar), the most severe form of
leishmaniasis, which is lethal if untreated. A few years ago, the re-sequencing and de novo …
leishmaniasis, which is lethal if untreated. A few years ago, the re-sequencing and de novo …
Identification of Immunoreactive Leishmania infantum Protein Antigens to Asymptomatic Dog Sera through Combined Immunoproteomics and Bioinformatics Analysis
Leishmania infantum is the etiologic agent of zoonotic visceral leishmaniasis (VL) in
countries in the Mediterranean basin, where dogs are the domestic reservoirs and represent …
countries in the Mediterranean basin, where dogs are the domestic reservoirs and represent …
Using proteomics as a powerful tool to develop a vaccine against Mediterranean visceral leishmaniasis
S Rashidi, K Kalantar, G Hatam - Journal of Parasitic Diseases, 2018 - Springer
Visceral leishmaniasis (VL) is a tropical infectious disease, which is called Mediterranean
visceral leishmaniasis (MVL) in the Mediterranean area. In spite of many attempts, no …
visceral leishmaniasis (MVL) in the Mediterranean area. In spite of many attempts, no …
Identification of novel leishmanicidal molecules by virtual and biochemical screenings targeting Leishmania eukaryotic translation initiation factor 4A
E Harigua-Souiai, YZ Abdelkrim… - PLoS Neglected …, 2018 - journals.plos.org
Leishmaniases are neglected parasitic diseases in spite of the major burden they inflict on
public health. The identification of novel drugs and targets constitutes a research priority. For …
public health. The identification of novel drugs and targets constitutes a research priority. For …
Quantitative secretome analysis unravels new secreted proteins in Amphotericin B resistant Leishmania donovani
Leishmaniasis is second most neglected disease after malaria and seems to be a worldwide
concern because of increased drug resistance and non-availability of approved vaccine …
concern because of increased drug resistance and non-availability of approved vaccine …