Pathogenesis of pneumonia and acute lung injury

ME Long, RK Mallampalli, JC Horowitz - Clinical Science, 2022 - portlandpress.com
Pneumonia and its sequelae, acute lung injury, present unique challenges for pulmonary
and critical care healthcare professionals, and these challenges have recently garnered …

The Role of Macrophages in Staphylococcus aureus Infection

GR Pidwill, JF Gibson, J Cole, SA Renshaw… - Frontiers in …, 2021 - frontiersin.org
Staphylococcus aureus is a member of the human commensal microflora that exists,
apparently benignly, at multiple sites on the host. However, as an opportunist pathogen it …

Neutrophil extracellular traps enhance macrophage killing of bacterial pathogens

AJ Monteith, JM Miller, CN Maxwell, WJ Chazin… - Science …, 2021 - science.org
Neutrophils and macrophages are critical to the innate immune response, but cooperative
mechanisms used by these cells to combat extracellular pathogens are not well understood …

A dual‐responsive antibiotic‐loaded nanoparticle specifically binds pathogens and overcomes antimicrobial‐resistant infections

M Ye, Y Zhao, Y Wang, M Zhao, N Yodsanit… - Advanced …, 2021 - Wiley Online Library
Antimicrobial resistant (AMR) infections are a growing threat to public health and there is a
general lack of development in new antibiotics. Here, a dextran‐coated stimuli‐responsive …

Mechanisms of Antibiotic Failure During Staphylococcus aureus Osteomyelitis

BD Gimza, JE Cassat - Frontiers in immunology, 2021 - frontiersin.org
Staphylococcus aureus is a highly successful Gram-positive pathogen capable of causing
both superficial and invasive, life-threatening diseases. Of the invasive disease …

Staphylococcal trafficking and infection—from 'nose to gut'and back

EJM Raineri, D Altulea… - FEMS microbiology …, 2022 - academic.oup.com
Staphylococcus aureus is an opportunistic human pathogen, which is a leading cause of
infections worldwide. The challenge in treating S. aureus infection is linked to the …

Inside job: Staphylococcus aureus host-pathogen interactions

J Horn, K Stelzner, T Rudel, M Fraunholz - International Journal of Medical …, 2018 - Elsevier
Staphylococcus aureus is a notorious opportunistic pathogen causing a plethora of
diseases. Recent research established that once phagocytosed by neutrophils and …

Identification and treatment of the Staphylococcus aureus reservoir in vivo

BGJ Surewaard, JF Deniset, FJ Zemp… - Journal of Experimental …, 2016 - rupress.org
Methicillin-resistant Staphylococcus aureus (MRSA) bacteremia is reaching epidemic
proportions causing morbidity, mortality, and chronic disease due to relapses, suggesting an …

Antimicrobial and anti-biofilm activity of tannic acid against Staphylococcus aureus

G Dong, H Liu, X Yu, X Zhang, H Lu… - Natural product …, 2018 - Taylor & Francis
Tannic acid, a rich of natural and process-derived phenolic compound, has been shown to
be an effective antagonist against viruses and bacteria. In this study, we determined the …

Antimicrobial Mechanisms of Macrophages and the Immune Evasion Strategies of Staphylococcus aureus

RS Flannagan, B Heit, DE Heinrichs - Pathogens, 2015 - mdpi.com
Habitually professional phagocytes, including macrophages, eradicate microbial invaders
from the human body without overt signs of infection. Despite this, there exist select bacteria …