The glutathione (GSH) system is considered to be one of the most powerful endogenous
antioxidant systems in the cardiovascular system due to its key contribution to detoxifying …

The anthracycline doxorubicin (DOX) is widely used in chemotherapy due to its efficacy in
fighting a wide range of cancers such as carcinomas, sarcomas and hematological cancers …

Doxorubicin (DOX)-induced toxicity and resistance are major obstacles in chemotherapeutic
approaches. Despite effective in the treatment of numerous malignancies, some clinicians …

Purpose Doxorubicin (DOX) is a highly active antineoplastic agent; however, its clinical use
is limited due to associated cardiotoxicity. This study was performed to evaluate the …

Dual-targeted nanoparticles have been increasingly used to realize greater anti-proliferation
effect by attacking double key sites of tumor cells. In order to retain nuclei inhibition effect …

Doxorubicin (DOX), is a very effective chemotherapeutic agent against cancer whose clinical
use is limited by toxicity. Different strategies have been proposed to attenuate toxicity …

Doxorubicin (DOX) is one of the most effective anti-cancer drugs, but its therapeutic efficacy
is greatly hampered by its non-specific delivery to the target tissue and the resultant …

Glomerular diseases remain the leading cause of chronic and end-stage kidney disease.
Significant advances in our understanding of human glomerular diseases have been …

A variety of epidemiological trials have suggested that higher intake of lycopene-containing
foods (primarily tomato products) or blood lycopene concentrations are associated with …

Anthracyclines (doxorubicin, daunorubicin, epirubicin, and idarubicin) are currently the most
effective group of anti-neoplastic drugs used in clinical practice. Of these, doxorubicin (also …