Reductions play a key role in organic synthesis, producing chiral products with new
functionalities. Enzymes can catalyse such reactions with exquisite stereo‐, regio‐and …

Asymmetric catalysis plays a key role in modern synthetic organic chemistry, with synthetic
catalysts and enzymes being the two available options. During the latter part of the last …

The study of non-natural biocatalytic transformations relies heavily on empirical methods,
such as directed evolution, for identifying improved variants. Although exceptionally …

Recent studies of multiple enzyme families collectively called ene-reductases (ERs) have
highlighted potential industrial applications of these biocatalysts in the production of fine and …

When challenged by a difficult reduction reaction, a chemist should always also consider
biocatalysis in synthesis planning. The inherent selectivity of enzymes has been known for …

The old yellow enzyme (OYE) family is a large group of flavin‐dependent redox biocatalysts
with major applications in the industrial reduction of activated alkenes. These enzymes have …

Abstract Flavin‐dependent 'ene'‐reductases (EREDs) are highly selective catalysts for the
asymmetric reduction of activated alkenes. This function is, however, limited to enones …

Redox reactions are essential to any currently known form of life and are at the core of a
majority of metabolic processes, such as cellular respiration or photosynthesis. As about …

Photoenzymes are biological catalysts that use light to convert starting materials into
products. These catalysts require photon absorption for each turnover, making quantum …

Ene-reductases from the 'Old Yellow Enzyme'family of flavoproteins catalyze the asymmetric
reduction of various α, β-unsaturated compounds at the expense of a nicotinamide cofactor …