Classic and exertional heatstroke

A Bouchama, B Abuyassin, C Lehe, O Laitano… - Nature Reviews …, 2022 - nature.com
In the past two decades, record-breaking heatwaves have caused an increasing number of
heat-related deaths, including heatstroke, globally. Heatstroke is a heat illness characterized …

High-intensity exercise and mitochondrial biogenesis: current controversies and future research directions

DJ Bishop, J Botella, AJ Genders, MJC Lee… - …, 2019 - journals.physiology.org
It is well established that different types of exercise can provide a powerful stimulus for
mitochondrial biogenesis. However, there are conflicting findings in the literature, and a …

Principles of exercise prescription, and how they influence exercise-induced changes of transcription factors and other regulators of mitochondrial biogenesis

C Granata, NA Jamnick, DJ Bishop - Sports Medicine, 2018 - Springer
Physical inactivity represents the fourth leading risk factor for mortality, and it has been
linked with a series of chronic disorders, the treatment of which absorbs~ 85% of healthcare …

The active grandparent hypothesis: Physical activity and the evolution of extended human healthspans and lifespans

DE Lieberman, TM Kistner, D Richard… - Proceedings of the …, 2021 - National Acad Sciences
The proximate mechanisms by which physical activity (PA) slows senescence and
decreases morbidity and mortality have been extensively documented. However, we lack an …

Network physiology of exercise: vision and perspectives

N Balagué, R Hristovski, M Almarcha… - Frontiers in …, 2020 - frontiersin.org
The basic theoretical assumptions of Exercise Physiology and its research directions,
strongly influenced by reductionism, may hamper the full potential of basic science …

Epigenetics in male reproduction: effect of paternal diet on sperm quality and offspring health

U Schagdarsurengin, K Steger - Nature Reviews Urology, 2016 - nature.com
Epigenetic inheritance and its underlying molecular mechanisms are among the most
intriguing areas of current biological and medical research. To date, studies have shown that …

Recent developments on the role of epigenetics in obesity and metabolic disease

SJ van Dijk, RL Tellam, JL Morrison, BS Muhlhausler… - Clinical …, 2015 - Springer
The increased prevalence of obesity and related comorbidities is a major public health
problem. While genetic factors undoubtedly play a role in determining individual …

[HTML][HTML] The applied implications of epigenetics in anxiety, affective and stress-related disorders-A review and synthesis on psychosocial stress, psychotherapy and …

MA Schiele, MG Gottschalk, K Domschke - Clinical psychology review, 2020 - Elsevier
Mental disorders are highly complex and multifactorial in origin, comprising an elaborate
interplay of genetic and environmental factors. Epigenetic mechanisms such as DNA …

Physical activity is associated with slower epigenetic ageing—Findings from the Rhineland study

FAU Fox, D Liu, MMB Breteler, NA Aziz - Aging Cell, 2023 - Wiley Online Library
Epigenetic ageing, ie, age‐associated changes in DNA methylation patterns, is a sensitive
marker of biological ageing, a major determinant of morbidity and functional decline. We …

Randomized controlled trial of increasing physical activity on objectively measured and self‐reported cognitive functioning among breast cancer survivors: The …

SJ Hartman, SH Nelson, E Myers, L Natarajan… - Cancer, 2018 - Wiley Online Library
BACKGROUND Increasing physical activity can improve cognition in healthy and cognitively
impaired adults; however, the benefits for cancer survivors are unknown. The current study …