A Look into Bunyavirales Genomes: Functions of Non-Structural (NS) Proteins
SS Leventhal, D Wilson, H Feldmann, DW Hawman - Viruses, 2021 - mdpi.com
In 2016, the Bunyavirales order was established by the International Committee on
Taxonomy of Viruses (ICTV) to incorporate the increasing number of related viruses across …
Taxonomy of Viruses (ICTV) to incorporate the increasing number of related viruses across …
Improved understanding of biorisk for research involving microbial modification using annotated sequences of concern
Regulation of research on microbes that cause disease in humans has historically been
focused on taxonomic lists of 'bad bugs'. However, given our increased knowledge of these …
focused on taxonomic lists of 'bad bugs'. However, given our increased knowledge of these …
Identification of a 1.4-kb-Long sequence located in the nsp12 and nsp13 coding regions of SARS-CoV-2 genomic RNA that mediates efficient viral RNA packaging
K Terasaki, K Narayanan, S Makino - Journal of virology, 2023 - Am Soc Microbiol
The specific packaging of the viral RNA genome into virus particles is an essential step in
the replication cycle of coronaviruses (CoVs). Using a single-cycle, replicable severe acute …
the replication cycle of coronaviruses (CoVs). Using a single-cycle, replicable severe acute …
Red-grouper nervous necrosis virus B1 protein inhibits fish IFN response by targeting Ser5-phosphorylated RNA polymerase II to promote viral replication
Y Qin, P Zhang, S Deng, W Guo, M Zhang, H Liu… - Fish & Shellfish …, 2023 - Elsevier
Nervous necrosis virus (NNV) could infect more than 200 fish species worldwide, with
almost 100% mortality in affected larvae and juvenile fish. Among different genotypes of …
almost 100% mortality in affected larvae and juvenile fish. Among different genotypes of …
RVFV virulence factor NSs triggers the mitochondrial MCL-1-BAK axis to activate pathogenic NLRP3 pyroptosis
Z Guan, H Li, C Zhang, Z Huang, M Ye, Y Zhang… - Plos …, 2024 - journals.plos.org
Infection of Rift Valley fever virus (RVFV), a highly pathogenic mosquito-borne zoonotic
virus, triggers severe inflammatory pathogenesis but the underlying mechanism of …
virus, triggers severe inflammatory pathogenesis but the underlying mechanism of …
Red-grouper nervous necrosis virus B2 protein negatively regulates fish interferon response by suppressing host transcription directed by RNA polymerase II
Y Qin, Y Wang, J Liu, Y Lu, X Liu - Aquaculture, 2021 - Elsevier
Nervous necrosis virus (NNV) infects more than 120 fish species worldwide and causes high
mortality and significant economic losses to the aquaculture industry. Among different …
mortality and significant economic losses to the aquaculture industry. Among different …
Current insights into human pathogenic phenuiviruses and the host immune system
Phenuiviruses are a class of segmented negative-sense single-stranded RNA viruses,
typically consisting of three RNA segments that encode four distinct proteins. The …
typically consisting of three RNA segments that encode four distinct proteins. The …
Characterization of the molecular interactions that govern the packaging of viral RNA segments into rift valley fever phlebovirus particles
B Tercero, K Narayanan, K Terasaki… - Journal of virology, 2021 - Am Soc Microbiol
Rift Valley fever phlebovirus (RVFV) has a single-stranded, negative-sense RNA genome,
consisting of L, M, and S segments. The virion carries two envelope glycoproteins, Gn and …
consisting of L, M, and S segments. The virion carries two envelope glycoproteins, Gn and …
Human genes with codon usage bias similar to that of the nonstructural protein 1 gene of influenza A viruses are conjointly involved in the infectious pathogenesis of …
K Nambou, M Anakpa, YS Tong - Genetica, 2022 - Springer
Molecular mechanisms of the non-structural protein 1 (NS1) in influenza A-induced
pathological changes remain ambiguous. This study explored the pathogenesis of human …
pathological changes remain ambiguous. This study explored the pathogenesis of human …
A single-cycle replicable Rift Valley fever phlebovirus vaccine carrying a mutated NSs confers full protection from lethal challenge in mice
K Terasaki, TL Juelich, JK Smith, B Kalveram… - Scientific reports, 2018 - nature.com
Rift Valley fever phlebovirus (RVFV) is a pathogen of Rift Valley fever, which is a mosquito-
borne zoonotic disease for domestic livestock and humans in African countries. Currently, no …
borne zoonotic disease for domestic livestock and humans in African countries. Currently, no …