The neutral aminopeptidases M1 alanyl aminopeptidase (PfM1AAP) and M17 leucine
aminopeptidase (PfM17LAP) of the human malaria parasite Plasmodium falciparum are …

Millions of people worldwide lie at the risk of parasitic protozoic infections that kill over a
million people each year. The rising inefficacy of conventional therapeutics to combat these …

There is a high demand for new drugs against malaria, which takes millions of lives
annually. The abuse of classical antimalarials from the late 1940's to the early 1980's has …

Malaria is a tropical disease with significant morbidity and mortality burden caused by
Plasmodium species in Africa, the Middle East, Asia, and South America. Pathogenic …

Malaria is an infectious disease causing vast mortality and morbidity worldwide. Although
antimalarial drugs are effective in several parts of the world, there is a serious threat to …

Introduction: Artocarpus altilis leaves extract has previously been reported as a potential
antimalarial drug. Inhibition concentration (IC 50) against P. falciparum and effective dose …

The persistence of drug resistance poses a significant obstacle to the advancement of
efficacious malaria treatments. The remarkable efficacy displayed by 1, 2, 3-triazole-based …

In an effort to develop a potent anti-malarial agent against Plasmodium falciparum, a
structure-guided virtual screening using an in-house library comprising 652 compounds was …

Background: The Plasmodium falciparum cysteine proteases, also known as falcipains, are
involved in different erythrocytic cycle processes of the malaria parasite, eg hydrolysis of …

The human malaria parasite Plasmodium falciparum proliferates in red blood cells following
repeated cycles of invasion, multiplication, and egress. P. falciparum serine repeat antigen 5 …