The hippocampus in major depression: evidence for the convergence of the bench and bedside in psychiatric research?

G MacQueen, T Frodl - Molecular psychiatry, 2011 - nature.com
Major depressive disorder (MDD) has until recently been conceptualized as an episodic
disorder associated with 'chemical imbalances' but no permanent brain changes. Evidence …

A quantitative meta‐analysis of fMRI studies in bipolar disorder

CH Chen, J Suckling, BR Lennox, C Ooi… - Bipolar …, 2011 - Wiley Online Library
Chen C‐H, Suckling J, Lennox BR, Ooi C, Bullmore ET. A quantitative meta‐analysis of fMRI
studies in bipolar disorder. Bipolar Disord 2011: 13: 1–15.© 2011 The Authors. Journal …

Subcortical volumetric abnormalities in bipolar disorder

DP Hibar, LT Westlye, TGM van Erp, J Rasmussen… - Molecular …, 2016 - nature.com
Considerable uncertainty exists about the defining brain changes associated with bipolar
disorder (BD). Understanding and quantifying the sources of uncertainty can help generate …

All roads lead to the default-mode network—global source of DMN abnormalities in major depressive disorder

A Scalabrini, B Vai, S Poletti, S Damiani… - …, 2020 - nature.com
Major depressive disorder (MDD) is a psychiatric disorder characterized by abnormal resting
state functional connectivity (rsFC) in various neural networks and especially in default …

Contrasting variability patterns in the default mode and sensorimotor networks balance in bipolar depression and mania

M Martino, P Magioncalda, Z Huang… - Proceedings of the …, 2016 - National Acad Sciences
Depressive and manic phases in bipolar disorder show opposite constellations of affective,
cognitive, and psychomotor symptoms. At a neural level, these may be related to …

Brain morphometric biomarkers distinguishing unipolar and bipolar depression: a voxel-based morphometry–pattern classification approach

R Redlich, JR Almeida, D Grotegerd, N Opel… - JAMA …, 2014 - jamanetwork.com
Importance The structural abnormalities in the brain that accurately differentiate unipolar
depression (UD) and bipolar depression (BD) remain unidentified. Objectives First, to …

Integrated neurobiology of bipolar disorder

V Maletic, C Raison - Frontiers in psychiatry, 2014 - frontiersin.org
From a neurobiological perspective there is no such thing as bipolar disorder. Rather, it is
almost certainly the case that many somewhat similar, but subtly different, pathological …

Amygdala volume changes in posttraumatic stress disorder in a large case-controlled veterans group

RA Morey, AL Gold, KS LaBar, SK Beall… - Archives of general …, 2012 - jamanetwork.com
Context Smaller hippocampal volumes are well established in posttraumatic stress disorder
(PTSD), but the relatively few studies of amygdala volume in PTSD have produced …

The role of lithium in the treatment of bipolar disorder: convergent evidence for neurotrophic effects as a unifying hypothesis

R Machado‐Vieira, HK Manji, CA Zarate Jr - Bipolar disorders, 2009 - Wiley Online Library
Lithium has been and continues to be the mainstay of bipolar disorder (BD)
pharmacotherapy for acute mood episodes, switch prevention, prophylactic treatment, and …

Effects of medication on neuroimaging findings in bipolar disorder: an updated review

DM Hafeman, KD Chang, AS Garrett… - Bipolar …, 2012 - Wiley Online Library
Hafeman DM, Chang KD, Garrett AS, Sanders EM, Phillips ML. Effects of medication on
neuroimaging findings in bipolar disorder: an updated review. Bipolar Disord 2012: 14: 375 …