Periodontal ligament stem cells (PDLSCs), which reside in the perivascular space of the
periodontium, possess characteristics of mesenchymal stem cells and are a promising tool …

Fibroblast growth factor (FGF) signaling controls fundamental processes such as
proliferation, differentiation and migration throughout mammalian development. Here we …

Since the advent of the generation of human induced pluripotent stem cells (hiPSCs),
numerous protocols have been developed to differentiate hiPSCs into cardiomyocytes and …

The mechanisms underlying the low efficiency of reprogramming somatic cells into induced
pluripotent stem (iPS) cells are poorly understood. There is a clear need to study whether …

Fibroblast growth factor (FGF) signaling is essential for normal and cancer biology.
Mammalian FGF family members participate in multiple signaling pathways by binding to …

Mouse epiblast stem cells (EpiSCs) are cultured with FGF2 and Activin A, like human
embryonic stem cells (hESCs), but the action of the associated pathways in EpiSCs has not …

Over the past two decades, human embryonic stem cells (hESCs) have gained attention due
to their pluripotent and proliferative ability which enables production of almost all cell types …

Pancreatic ductal adenocarcinoma (PDAC) carries a dismal prognosis and lacks a human
cell model of early disease progression. When human PDAC cells are injected into …

The highly regenerative capacity of the human adult oral mucosa suggests the existence of
a robust stem cell (SC) population in its lamina propria (OMLP). The purpose of this study …

Precise self-renewal of the germ cell lineage is fundamental to fertility and reproductive
success. The early precursors for the germ lineage, primordial germ cells (PGCs), survive …