Influenza vaccines could be improved by platforms inducing cross-reactive immunity.
Immunodominance of the influenza hemagglutinin (HA) head in currently licensed vaccines …

The overarching logos of mammalian memory B cells (MBCs) is to cache the potential for
enhanced antibody production upon secondary exposure to cognate antigenic …

Many rigorous studies have shown that early childhood infections leave a lasting imprint on
the immune system. The understanding of this phenomenon has expanded significantly …

Defending against future pandemics requires vaccine platforms that protect across a range
of related pathogens. Nanoscale patterning can be used to address this issue. Here, we …

Immune imprinting is a phenomenon in which prior antigenic experiences influence
responses to subsequent infection or vaccination1, 2. The effects of immune imprinting on …

Nanoparticle vaccines based on H. pylori ferritin are increasingly used as a vaccine platform
for many pathogens, including RSV, influenza, and SARS-CoV-2. They have been found to …

Commercial influenza virus vaccines often elicit strain-specific immune responses and have
difficulties preventing illness caused by antigenically drifted viral variants. In the last 20 …

Despite the availability of licensed vaccines, influenza causes considerable morbidity and
mortality worldwide. Current influenza vaccines elicit an immune response that primarily …

Introduction Current approved COVID-19 vaccines, notably mRNA and adenoviral vectored
technologies, still fail to fully protect against infection and transmission of various SARS-CoV …

Participants between the ages of 10–86 years old were vaccinated with split-inactivated
influenza vaccine (Fluzone®) in six consecutive influenza seasons from 2016–2017 to 2021 …