Fibrotic interstitial lung diseases (fILDs) have poor survival rates and lack effective therapies.
Despite evidence for immune mechanisms in lung fibrosis, immunotherapies have been …

Endometriosis negatively impacts the health-related quality of life of 190 million women
worldwide. Novel advances in nonhormonal treatments for this debilitating condition are …

When dysregulated, skin fibrosis can lead to a multitude of pathologies. We provide a
framework for understanding the wide clinical spectrum, mechanisms, and management of …

This study aims to investigate applicable robust biomarkers that can improve prognostic
predictions for colorectal liver metastasis (CRLM) patients receiving simultaneous resection …

Pancreatic ductal adenocarcinoma (PDAC) is an extremely lethal cancer that accounts for
over 90% of all pancreatic cancer cases. With a 5-year survival rate of only 13%, PDAC has …

Vascular calcification (VC) is considered a common pathological process in various vascular
diseases. Accumulating studies have confirmed that VC is involved in the inflammatory …

Coccidioidomycosis, or Valley fever, is a lung disease caused by inhalation of Coccidioides
fungi, prevalent in the Southwestern United States, Mexico, and parts of Central and South …

Macrophages are instrumental in maintaining tissue homeostasis, modulating inflammation,
and driving regeneration. The advent of omics techniques has led to the identification of …

Aging is a complex biological process that involves the gradual decline of cellular, tissue,
and organ functions. In kidney, aging manifests as tubular atrophy, glomerulosclerosis, and …

Background Cardiac fibrosis after myocardial infarction (MI) has been considered an
important part of cardiac pathological remodeling. Immune cells, especially macrophages …