Advances in the diagnosis of human schistosomiasis

KGAD Weerakoon, GN Gobert, P Cai… - Clinical microbiology …, 2015 - Am Soc Microbiol
Schistosomiasis is a major neglected tropical disease that afflicts more than 240 million
people, including many children and young adults, in the tropics and subtropics. The …

[HTML][HTML] Serological approaches for the diagnosis of schistosomiasis–A review

R Hinz, NG Schwarz, A Hahn, H Frickmann - Molecular and Cellular …, 2017 - Elsevier
Schistosomiasis is a common disease in endemic areas of Sub-Saharan Africa, South
America and Asia. It is rare in Europe, mainly imported from endemic countries due to …

[HTML][HTML] A five-country evaluation of a point-of-care circulating cathodic antigen urine assay for the prevalence of Schistosoma mansoni

DG Colley, S Binder, C Campbell, CH King… - The American journal …, 2013 - ncbi.nlm.nih.gov
We evaluated a commercial point-of-care circulating cathodic antigen (POC-CCA) test for
assessing Schistosoma mansoni infection prevalence in areas at risk. Overall, 4,405 school …

Tools for diagnosis, monitoring and screening of Schistosoma infections utilizing lateral-flow based assays and upconverting phosphor labels

PLAM Corstjens, CJ De Dood, D Kornelis, EMTK Fat… - Parasitology, 2014 - cambridge.org
The potential of various quantitative lateral flow (LF) based assays utilizing up-converting
phosphor (UCP) reporters for the diagnosis of schistosomiasis is reviewed including recent …

[HTML][HTML] Sensitivity and Specificity of Multiple Kato-Katz Thick Smears and a Circulating Cathodic Antigen Test for Schistosoma mansoni Diagnosis Pre- and Post …

PHL Lamberton, NB Kabatereine… - PLoS neglected …, 2014 - journals.plos.org
Background Two Kato-Katz thick smears (Kato-Katzs) from a single stool are currently
recommended for diagnosing Schistosoma mansoni infections to map areas for intervention …

[HTML][HTML] From innovation to application: Social–ecological context, diagnostics, drugs and integrated control of schistosomiasis

J Utzinger, EK N'Goran, CR Caffrey, J Keiser - Acta tropica, 2011 - Elsevier
Compared to malaria, tuberculosis and HIV/AIDS, schistosomiasis remains a truly neglected
tropical disease. Schistosomiasis, perhaps more than any other disease, is entrenched in …

Up-Converting Phosphor Technology-Based Lateral Flow Assay for Detection of Schistosoma Circulating Anodic Antigen in Serum

PLAM Corstjens, L van Lieshout… - Journal of clinical …, 2008 - Am Soc Microbiol
Schistosoma sp. circular anodic antigen (CAA) serum concentrations reflect actual worm
burden in a patient and are a valuable tool for population screening and epidemiological …

Circulating antigen tests and urine reagent strips for diagnosis of active schistosomiasis in endemic areas

EA Ochodo, G Gopalakrishna, B Spek… - Cochrane Database …, 2015 - cochranelibrary.com
Background Point‐of‐care (POC) tests for diagnosing schistosomiasis include tests based
on circulating antigen detection and urine reagent strip tests. If they had sufficient diagnostic …

Application of a circulating-cathodic-antigen (CCA) strip test and real-time PCR, in comparison with microscopy, for the detection of Schistosoma haematobium in …

BB Obeng, YA Aryeetey, CJ De Dood… - Annals of Tropical …, 2008 - Taylor & Francis
In the detection of parasitic infection, the traditional methods based on microscopy often
have low sensitivity and/or specificity compared with the newer, molecular tests. An assay …

[HTML][HTML] DNA diagnostics for schistosomiasis control

KG Weerakoon, CA Gordon, DP McManus - Tropical medicine and …, 2018 - mdpi.com
Despite extensive efforts over the last few decades, the global disease burden of
schistosomiasis still remains unacceptably high. This could partly be attributed to the lack of …