Significant reductions in the extent of acute injury in the CNS can be achieved by exposure
to different preconditioning stimuli, but the duration of the induced protective phenotype is …

Although both preclinical and clinical conditioning studies in heart and brain lead the field of
conditioning medicine, investigations of retinal conditioning still number more than 100. In …

The vascular leakage in diabetic retinopathy leads to macular edema and vision loss.
Although astrocyte play an important role in regulating blood-brain barrier integrity in the …

Background Retinal ischaemia is a common feature shared by numerous eye diseases.
Ischaemic insult leads to retinal dysfunction and neuronal death. Lycium barbarum …

Pregabalin is the first drug to receive FDA approval for treating diabetic neuropathic pain.
This study investigated the neuroprotective effect of pregabalin in an experimental model of …

Ischemic conditioning inhibits oxidative stress and inflammatory response in diabetes.
However, whether limb remote ischemic conditioning (LRIC) has beneficial effects on …

Ischemic conditioning, the application of a mild ischemic stimulus to an ischemia-sensitive
structure like the heart or brain either before (preconditioning) or after (postconditioning) its …

Diabetic retinopathy is one of the main microvascular complications of diabetes and remains
one of the leading causes of blindness worldwide. Recent studies have revealed an …

Metabolic syndrome is a disorder characterized by a constellation of clinical findings such as
elevated blood glucose, hyperinsulinemia, dyslipidemia, hypertension, and obesity. A …

Diabetic retinopathy is a leading cause of reduced visual acuity and acquired blindness.
Available treatments are not completely effective. We analyzed the effect of environmental …