Pharmacomicrobiomics in pediatric oncology: the complex interplay between commonly used drugs and gut microbiome

D Leardini, F Venturelli, F Baccelli, S Cerasi… - International Journal of …, 2022 - mdpi.com
The gut microbiome (GM) has emerged in the last few years as a main character in several
diseases. In pediatric oncological patients, GM has a role in promoting the disease …

Circulating T cell profiles associate with enterotype signatures underlying hematological malignancy relapses

N Vallet, M Salmona, J Malet-Villemagne, M Bredel… - Cell Host & Microbe, 2023 - cell.com
Early administration of azithromycin after allogeneic hematopoietic stem cell transplantation
was shown to increase the relapse of hematological malignancies. To determine the impact …

Randomized double-blind phase II trial of fecal microbiota transplantation versus placebo in allogeneic hematopoietic cell transplantation and AML

A Rashidi, M Ebadi, TU Rehman… - Journal of Clinical …, 2023 - ascopubs.org
PURPOSE Gut microbiota injury in allogeneic hematopoietic cell transplantation (HCT)
recipients and patients with AML has been associated with adverse clinical outcomes …

Gut microbiota, microbiota‐derived metabolites, and graft‐versus‐host disease

XY Yue, H Zhou, SF Wang, X Chen… - Cancer Medicine, 2024 - Wiley Online Library
Allogeneic hematopoietic stem cell transplantation is one of the most effective treatment
strategies for leukemia, lymphoma, and other hematologic malignancies. However, graft …

Fecal transplantation in hematopoietic transplantation

JU Peled, MRM van den Brink - Journal of Clinical Oncology, 2023 - ascopubs.org
In the companion to this article, Rashidi et al 1 report the results of a randomized trial of fecal
microbiota transplantation (FMT) in recipients of induction chemotherapy for acute leukemia …

Loss of microbiota-derived protective metabolites after neutropenic fever

A Rashidi, M Ebadi, TU Rehman, H Elhusseini… - Scientific reports, 2022 - nature.com
Neutropenic fever (NF) is a common complication of chemotherapy in patients with cancer
which often prolongs hospitalization and worsens the quality of life. Although an empiric …

Compilation of longitudinal gut microbiome, serum metabolome, and clinical data in acute myeloid leukemia

A Rashidi, M Ebadi, TU Rehman, H Elhusseini… - Scientific Data, 2022 - nature.com
Induction chemotherapy for patients with acute myeloid leukemia (AML) is a unique clinical
scenario. These patients spend several weeks in the hospital, receiving multiple antibiotics …

Contribution of the oral and gastrointestinal microbiomes to bloodstream infections in Leukemia patients

S McMahon, P Sahasrabhojane, J Kim… - Microbiology …, 2023 - Am Soc Microbiol
Bloodstream infections (BSIs) pose a significant mortality risk for acute myeloid leukemia
(AML) patients. It has been previously reported that intestinal domination (> 30% relative …

Distinct enterotypes and dysbiosis: unraveling gut microbiota in pulmonary and critical care medicine inpatients

N Li, G Tan, Z Xie, W Chen, Z Yang, Z Wang, S Liu… - Respiratory …, 2024 - Springer
Background The gut-lung axis, pivotal for respiratory health, is inadequately explored in
pulmonary and critical care medicine (PCCM) inpatients. Methods Examining PCCM …

Dysbiosis of the gut microbiota is associated with in-hospital mortality in patients with antibiotic-associated diarrhoea: A metagenomic analysis

MH Choi, D Kim, KH Lee, HJ Kim, WJ Sul… - International journal of …, 2024 - Elsevier
Background The increasing incidence of antibiotic-associated diarrhoea (AAD) is a serious
health care problem. Dysbiosis of the gut microbiota is suspected to play a role in the …