Comparative genomics has recently provided unprecedented insights into the biology and
evolution of the fungal lineage. In the postgenomics era, a major research interest focuses …

In eukaryotic cells, the genome is organized in the form of chromatin composed of DNA and
histones that organize and regulate gene expression. The dysregulation of chromatin …

During cell division, remodelling of the nuclear envelope enables chromosome segregation
by the mitotic spindle. The reformation of sealed nuclei requires ESCRTs (endosomal …

In eukaryotes, heterochromatin is generally located at the nuclear periphery. This study
investigates the biological significance of perinuclear positioning for heterochromatin …

The establishment of centromere-specific CENP-A chromatin is influenced by epigenetic
and genetic processes. Central domain sequences from fission yeast centromeres are …

The number, distribution, and composition of nuclear pore complexes (NPCs) in the nuclear
envelope varies between cell types and changes during cellular differentiation and in …

Heterochromatin is generally associated with the nuclear periphery, but how the spatial
organization of heterochromatin is regulated to ensure epigenetic silencing remains unclear …

Telomere anchoring to nuclear envelope (NE) is a key feature of nuclear genome
architecture. Peripheral localization of telomeres is important for chromatin silencing …

The nuclear envelope (NE) consists of the inner and outer nuclear membranes (INM and
ONM), and the nuclear pore complex (NPC), which penetrates the double membrane. ONM …

Regulation by the small modifier SUMO is heavily dependent on spatial control of enzymes
that mediate the attachment and removal of SUMO on substrate proteins. Here, we show that …