As analytical interests have become targeted on sensitive detection of objects of a tiny size
and volume, various fields in analytical chemistry have been developed to overcome …

Antimicrobial peptides (AMPs) are broad spectrum antibiotics that selectively target bacteria.
Here we investigate the activity of human AMP LL37 against Escherichia coli by integrating …

Antimicrobial peptides (AMPs) are promising in the fight against increasing bacterial
resistance, but the development of AMPs with enhanced activity requires a thorough …

Patterned deposition and 3D fabrication techniques have enabled the use of hydrogels for a
number of applications including microfluidics, sensors, separations, and tissue engineering …

Reconstruction of large bone defects remains a clinical challenge because current
approaches involving surgery and bone grafting often do not yield satisfactory outcomes. For …

Replica molding is a well-established technique to fabricate surfaces with micro-patterns.
Double replica molding of polydimethylsiloxane (PDMS) was developed to fabricate bio …

Beta-lactams comprise one of the earliest classes of antibiotic therapies. These molecules
covalently inhibit enzymes from the family of penicillin-binding proteins (PBPs), which are …

For in vivo, single-cell imaging bacterial cells are commonly immobilised via physical
confinement or surface attachment. Different surface attachment methods have been used …

Singularity biology is a scientific field that targets drastic state changes in multicellular
systems, aiming to discover the key cells that induce the state change and investigate the …

Bacteria primarily live in structured environments, such as colonies and biofilms, attached to
surfaces or growing within soft tissues. They are engaged in local competitive and …