Background and aim Clinical evidence for early identification and diagnosis of liver cirrhosis
(LC) caused by different types of liver disease is limited. We investigated this topic through a …

Background Treatment-resistant depression (TRD) results in huge healthcare costs and
poor patient clinical outcomes. Most studies have adopted a “candidate mechanism” …

Major depressive disorder (MDD) involves systemic changes in peripheral blood and gut
microbiota, but the current understanding is incomplete. Herein, we conducted a multi-omics …

Major depressive disorder (MDD) involves changes in lipid metabolism, but previous
findings are contradictory. Mesencephalic astrocyte-derived neurotrophic factor (MANF) is …

Background Cardiovascular disease (CVD) and depression have a bidirectional
association, with inflammation and metabolic factors being common important triggers for …

Both metabolic syndrome (MetS) and subclinical hypothyroidism (SCH) are prevalent in
major depressive disorder (MDD) patients. However, their relationship in this population …

Background Children and adolescents with major depressive disorder (MDD) are at
increased risk for premature cardiovascular disease (CVD). Whether adolescents with MDD …

The pathogenesis of major depressive disorder (MDD) involves lipid metabolism. Our earlier
research also revealed that MDD patients had much lower total cholesterol (TC) …

Background Research assessing lipid levels in individuals diagnosed with post-traumatic
stress disorder (PTSD) has yielded mixed results. This study aimed to employ meta-analytic …

Context Current evidence on the effect of a low-fat (LF) diet on depression scores has been
inconsistent. Objective To explore the effect of an LF diet on depression scores of adults by …