Metagenomics and marker gene approaches, coupled with high-throughput sequencing
technologies, have revolutionized the field of microbial ecology. Metagenomics is a culture …

In recent years, the use of longer range read data combined with advances in assembly
algorithms has stimulated big improvements in the contiguity and quality of genome …

Despite recent advances in metagenomic binning, reconstruction of microbial species from
metagenomics data remains challenging. Here we develop variational autoencoders for …

Background Recovering individual genomes from metagenomic datasets allows access to
uncultivated microbial populations that may have important roles in natural and engineered …

Generating the raw data for a de novo genome assembly project for a target eukaryotic
species is relatively easy. This democratization of access to large-scale data has allowed …

Background Shotgun metagenomics based on untargeted sequencing can explore the
taxonomic profile and the function of unknown microorganisms in samples, and complement …

Advanced age is characterized by several changes, one of which is the impairment of the
homeostasis of intestinal microbiota. These alterations critically influence host health and …

Background Microbes are main drivers of biogeochemical cycles in oceans and lakes.
Although the genome is a foundation for understanding the metabolism, ecology and …

Background The new research field of metagenomics is providing exciting insights into
various, previously unclassified ecological systems. Next-generation sequencing …

Characterizing the taxonomic diversity of microbial communities is one of the primary
objectives of metagenomic studies. Taxonomic analysis of microbial communities, a process …