Abundance and stability as common properties of allergens

ACY Foo, GA Mueller - Frontiers in Allergy, 2021 - frontiersin.org
There have been many attempts to identify common biophysical properties which
differentiate allergens from their non-immunogenic counterparts. This review will focus on …

A transcriptomic atlas of Aedes aegypti reveals detailed functional organization of major body parts and gut regional specializations in sugar-fed and blood-fed adult …

B Hixson, XL Bing, X Yang, A Bonfini, P Nagy… - Elife, 2022 - elifesciences.org
Mosquitoes transmit numerous pathogens, but large gaps remain in our understanding of
their physiology. To facilitate explorations of mosquito biology, we have created Aegypti …

Implications of mosquito metabolism on vector competence

L Gao, W Yang, J Wang - Insect Science, 2024 - Wiley Online Library
Mosquito‐borne diseases (MBDs) annually kill nearly half a million people. Due to the lack
of effective vaccines and drugs on most MBDs, disease prevention relies primarily on …

Albumin Proteins as Delivery Vehicles for PFAS Contaminants into Respiratory Membranes

ES Pye, SE Wallace, DG Marangoni, ACY Foo - ACS omega, 2023 - ACS Publications
Poly-and perfluoroalkyl substances (PFAS) are a family of chemicals that have been used in
a wide range of commercial products. While their use is declining, the prevalence of PFAS …

Identification of Aedes aegypti salivary gland proteins interacting with human immune receptor proteins

E Gavor, YK Choong, Y Liu, J Pompon… - PLoS Neglected …, 2022 - journals.plos.org
Mosquito saliva proteins modulate the human immune and hemostatic systems and control
mosquito-borne pathogenic infections. One mechanism through which mosquito proteins …

Structural and ligand binding analysis of the pet allergens Can f 1 and Fel d 7

J Min, ACY Foo, SA Gabel, L Perera, EF DeRose… - Frontiers in …, 2023 - frontiersin.org
Introduction Pet lipocalins are respiratory allergens with a central hydrophobic ligand-
binding cavity called a calyx. Molecules carried in the calyx by allergens are suggested to …

Production and Release of Proinflammatory Mediators by the Cockroach Allergen Bla g 1 via a Shared Membrane-Destabilization Mechanism

ACY Foo, ML Edin, WC Lin, FB Lih, SA Gabel… - Biochemistry, 2024 - ACS Publications
The cockroach allergen Bla g 1 encloses an exceptionally large hydrophobic cavity, which
allows it to bind and deliver unsaturated fatty acid ligands. Bla g 1-mediated delivery of …

Two avian Plasmodium species trigger different transcriptional responses on their vector Culex pipiens

M Garrigós, G Ylla, J Martínez‐de la Puente… - Molecular …, 2023 - Wiley Online Library
Malaria is a mosquito‐borne disease caused by protozoans of the genus Plasmodium that
affects both humans and wildlife. The fitness consequences of infections by avian malaria …

Expanding the antiviral potential of the mosquito lipid‐transfer protein AEG12 against SARS‐CoV‐2 using hydrophobic antiviral ligands

ACY Foo, BAP Lafont, GA Mueller - FEBS letters, 2022 - Wiley Online Library
The mosquito protein AEG12 encompasses a large (~ 3800 Å3) hydrophobic cavity which
binds and delivers unsaturated fatty acids into biological membranes, allowing it to lyse cells …

Transcriptome Analysis Reveals Early Hemocyte Responses upon In Vivo Stimulation with LPS in the Stick Insect Bacillus rossius (Rossi, 1788)

C Bidoli, A Miccoli, F Buonocore, AM Fausto, M Gerdol… - Insects, 2022 - mdpi.com
Simple Summary Non-model insect species such as B. rossius suffer from a profound gap of
knowledge regarding the temporal progression of physiological responses following the …