Molecular imaging–based dose painting: A novel paradigm for radiation therapy prescription

SM Bentzen, V Gregoire - Seminars in radiation oncology, 2011 - Elsevier
Dose painting is the prescription of a nonuniform radiation dose distribution to the target
volume based on functional or molecular images shown to indicate the local risk of relapse …

Advances in radiotherapy for head and neck cancer

V Grégoire, JA Langendijk, S Nuyts - Journal of Clinical Oncology, 2015 - ascopubs.org
Over the last few decades, significant improvements have been made in the radiotherapy
(RT) treatment of head and neck malignancies. The progressive introduction of intensity …

A gradient-based method for segmenting FDG-PET images: methodology and validation

X Geets, JA Lee, A Bol, M Lonneux… - European journal of …, 2007 - Springer
Purpose A new gradient-based method for segmenting FDG-PET images is described and
validated. Methods The proposed method relies on the watershed transform and …

Adaptive dose painting by numbers for head-and-neck cancer

F Duprez, W De Neve, W De Gersem, M Coghe… - International Journal of …, 2011 - Elsevier
PURPOSE: To investigate the feasibility of adaptive intensity-modulated radiation therapy
(IMRT) using dose painting by numbers (DPBN) for head-and-neck cancer. METHODS AND …

PET-based treatment planning in radiotherapy: a new standard?

V Grégoire, K Haustermans, X Geets… - Journal of Nuclear …, 2007 - Soc Nuclear Med
Molecular imaging, in particular, PET, has brought an additional dimension to management
for patients with cancer. 18 F-FDG, which is the most widely available tracer, has been …

Positron emission tomography-guided, focal-dose escalation using intensity-modulated radiotherapy for head and neck cancer

I Madani, W Duthoy, C Derie, W De Gersem… - International Journal of …, 2007 - Elsevier
PURPOSE: To assess the feasibility of intensity-modulated radiotherapy (IMRT) using
positron emission tomography (PET)-guided dose escalation, and to determine the …

Comparison of 12 deformable registration strategies in adaptive radiation therapy for the treatment of head and neck tumors

P Castadot, JA Lee, A Parraga, X Geets, B Macq… - Radiotherapy and …, 2008 - Elsevier
BACKGROUND AND PURPOSE: Weight loss, tumor shrinkage, and tissue edema induce
substantial modification of patient's anatomy during head and neck (HN) radiotherapy (RT) …

The role of replanning in fractionated intensity modulated radiotherapy for nasopharyngeal carcinoma

L Zhao, Q Wan, Y Zhou, X Deng, C Xie, S Wu - Radiotherapy and Oncology, 2011 - Elsevier
BACKGROUND AND PURPOSE: Anatomic changing frequently occurred during
fractionated radiotherapy. The aims of this study were to model the potential benefit of …

Practical integration of [18F]-FDG-PET and PET-CT in the planning of radiotherapy for non-small cell lung cancer (NSCLC): the technical basis, ICRU-target volumes …

U Nestle, S Kremp, AL Grosu - Radiotherapy and oncology, 2006 - Elsevier
The value of positron emission tomography using [18F]-fluoro-deoxy-glucose (FDG-PET) for
pretherapeutic evaluation of patients with non-small cell lung cancer (NSCLC) is beyond …

Adaptive biological image-guided IMRT with anatomic and functional imaging in pharyngo-laryngeal tumors: impact on target volume delineation and dose distribution …

X Geets, M Tomsej, JA Lee, T Duprez, E Coche… - Radiotherapy and …, 2007 - Elsevier
BACKGROUND AND PURPOSE: Adaptive image-guided IMRT appears to be a promising
approach for dose escalation in pharyngo-laryngeal tumors. In this framework, we assessed …