Micro (nano) plastics pollution and human health: How plastics can induce carcinogenesis to humans?
Abstract Microplastics (MPs) and nanoplastics (NPs) are key indicators of the plasticine era,
widely spread across different ecosystems. MPs and NPs become global stressors due to …
widely spread across different ecosystems. MPs and NPs become global stressors due to …
[HTML][HTML] Immunosuppression in tumor immune microenvironment and its optimization from CAR-T cell therapy
Z Liu, Z Zhou, Q Dang, H Xu, J Lv, H Li, X Han - Theranostics, 2022 - ncbi.nlm.nih.gov
Chimeric antigen receptor (CAR)-T cell therapy represents a landmark advance in
personalized cancer treatment. CAR-T strategy generally engineers T cells from a specific …
personalized cancer treatment. CAR-T strategy generally engineers T cells from a specific …
[HTML][HTML] Organs-on-chips technologies–A guide from disease models to opportunities for drug development
Current in-vitro 2D cultures and animal models present severe limitations in recapitulating
human physiopathology with striking discrepancies in estimating drug efficacy and side …
human physiopathology with striking discrepancies in estimating drug efficacy and side …
[HTML][HTML] Targeting the tumor microenvironment in B-cell lymphoma: challenges and opportunities
Y Liu, X Zhou, X Wang - Journal of Hematology & Oncology, 2021 - Springer
B-cell lymphoma is a group of hematological malignancies with high clinical and biological
heterogeneity. The pathogenesis of B-cell lymphoma involves a complex interaction …
heterogeneity. The pathogenesis of B-cell lymphoma involves a complex interaction …
Immunotherapy discovery on tumor organoid-on-a-chip platforms that recapitulate the tumor microenvironment
Cancer immunotherapy has achieved remarkable success over the past decade by
modulating patients' own immune systems and unleashing pre-existing immunity. However …
modulating patients' own immune systems and unleashing pre-existing immunity. However …
Emerging tumor-on-chips with electrochemical biosensors
Cancer, one of the most dangerous diseases with a high mortality rate, has attracted much
attention and interest. Advances in tissue engineering and microfluidics have led to the …
attention and interest. Advances in tissue engineering and microfluidics have led to the …
[HTML][HTML] Fusobacterium nucleatum Acts as a Pro-carcinogenic Bacterium in Colorectal Cancer: From Association to Causality
S Wang, Y Liu, J Li, L Zhao, W Yan, B Lin… - Frontiers in Cell and …, 2021 - frontiersin.org
Colorectal cancer (CRC) is a common cancer worldwide with complex etiology.
Fusobacterium nucleatum (F. nucleatum), an oral symbiotic bacterium, has been linked with …
Fusobacterium nucleatum (F. nucleatum), an oral symbiotic bacterium, has been linked with …
New strategy for promoting vascularization in tumor spheroids in a microfluidic assay
Z Wan, MA Floryan, MF Coughlin… - Advanced …, 2023 - Wiley Online Library
Previous studies have developed vascularized tumor spheroid models to demonstrate the
impact of intravascular flow on tumor progression and treatment. However, these models …
impact of intravascular flow on tumor progression and treatment. However, these models …
[HTML][HTML] Recent advances of organ-on-a-chip in cancer modeling research
X Liu, Q Su, X Zhang, W Yang, J Ning, K Jia, J Xin, H Li… - Biosensors, 2022 - mdpi.com
Although many studies have focused on oncology and therapeutics in cancer, cancer
remains one of the leading causes of death worldwide. Due to the unclear molecular …
remains one of the leading causes of death worldwide. Due to the unclear molecular …
[HTML][HTML] Engineering prostate cancer in vitro: what does it take?
A key challenge in the clinical management and cause of treatment failure of prostate cancer
(PCa) is its molecular, cellular and clinical heterogeneity. Modelling systems that fully …
(PCa) is its molecular, cellular and clinical heterogeneity. Modelling systems that fully …