Diabetic kidney disease is the leading cause of kidney failure worldwide; in the USA, it
accounts for over 50% of individuals entering dialysis or transplant programmes. Unlike …

Loss of normal kidney function affects more than 10% of the population and contributes to
morbidity and mortality. Kidney diseases are currently treated with immunosuppressive …

Chronic kidney disease (CKD) is defined by persistent urine abnormalities, structural
abnormalities or impaired excretory renal function suggestive of a loss of functional …

Lupus nephritis (LN) is a frequent and severe manifestation of SLE. Along the decades, the
epidemiology of LN and its clinical presentation have been changing. However, even …

Despite recent advances in the management of chronic kidney disease (CKD), morbidity
and mortality rates in these patients remain high. While pressure-mediated injury is a well …

For nearly 50 years the proximal tubule (PT) has been known to reabsorb, process, and
either catabolize or transcytose albumin from the glomerular filtrate. Innovative techniques …

Amplification of oxidative stress is present since the early stages of chronic kidney disease
(CKD), holding a key position in the pathogenesis of renal failure. Induction of renal pro …

Significance: A common link between all forms of acute and chronic kidney injuries,
regardless of species, is enhanced generation of reactive oxygen species (ROS) and …

Background Change in albuminuria has strong biological plausibility as a surrogate
endpoint for progression of chronic kidney disease, but empirical evidence to support its …

The new respiratory infectious disease coronavirus disease 2019 (COVID-19) that
originated in Wuhan, China, in December 2019 and caused by a new strain of zoonotic …