The Gateway Hypothesis of substance abuse: developmental, biological and societal perspectives

D Kandel, E Kandel - Acta Paediatrica, 2015 - Wiley Online Library
Abstract The Gateway Hypothesis describes how tobacco or alcohol use precedes
marijuana and other illicit drug use. We review the epidemiological data, explore the …

The etiologic, theory-based, ontogenetic hierarchical framework of alcohol use disorder: A translational systematic review of reviews.

CL Boness, AL Watts, KN Moeller, KJ Sher - Psychological Bulletin, 2021 - psycnet.apa.org
Abstract Modern nosologies (eg, International Classification of Diseases, 11th edition [ICD-
11], Diagnostic and Statistical Manual of Mental Disorders, 5th edition [DSM–5]) for alcohol …

Early adolescent patterns of alcohol, cigarettes, and marijuana polysubstance use and young adult substance use outcomes in a nationally representative sample

HB Moss, CM Chen, H Yi - Drug and alcohol dependence, 2014 - Elsevier
Background Alcohol, tobacco and marijuana are the most commonly used drugs by
adolescents in the US However, little is known about the patterning of early adolescent …

The genetic epidemiology of substance use disorder: A review

EC Prom-Wormley, J Ebejer, DM Dick… - Drug and alcohol …, 2017 - Elsevier
Background Substance use disorder (SUD) remains a significant public health issue. A
greater understanding of how genes and environment interact to regulate phenotypes …

The addiction risk factor: A unitary genetic vulnerability characterizes substance use disorders and their associations with common correlates

AS Hatoum, EC Johnson, SMC Colbert… - …, 2022 - nature.com
Substance use disorders commonly co-occur with one another and with other psychiatric
disorders. They share common features including high impulsivity, negative affect, and lower …

Vaping as a catalyst for smoking? An initial model on the initiation of electronic cigarette use and the transition to tobacco smoking among adolescents

S Schneider, K Diehl - Nicotine & Tobacco Research, 2016 - academic.oup.com
Introduction: The popularity of electronic cigarettes (e-cigarettes) among adolescents is
growing worldwide. A more accurate model than the much discussed but inadequate …

The relationship between tobacco and cannabis use: a review

A Lemyre, N Poliakova, RE Bélanger - Substance Use & Misuse, 2019 - Taylor & Francis
Background: Based on the prevalence and health implications of tobacco and cannabis use,
aiming to reduce their use, especially among youth, is a sound objective at both the …

Age of initiation and substance use progression: A multivariate latent growth analysis.

LS Richmond-Rakerd, WS Slutske… - Psychology of Addictive …, 2017 - psycnet.apa.org
An individual's age at first substance use may be associated with their risk for progression
toward heavier substance involvement. To our knowledge, however, no studies within …

Mechanisms and genetic factors underlying co-use of nicotine and alcohol or other drugs of abuse

SJ Cross, S Lotfipour, FM Leslie - The American Journal of Drug …, 2017 - Taylor & Francis
Concurrent use of tobacco and alcohol or psychostimulants represents a major public health
concern, with use of one substance influencing consumption of the other. Co-abuse of these …

The collaborative study on the genetics of alcoholism: Sample and clinical data

DM Dick, E Balcke, V McCutcheon… - Genes, Brain and …, 2023 - Wiley Online Library
The collaborative study on the genetics of alcoholism (COGA) is a multi‐site,
multidisciplinary project with the goal of identifying how genes are involved in alcohol use …