Importance Chronic pancreatitis (CP) is a chronic inflammatory and fibrotic disease of the
pancreas with a prevalence of 42 to 73 per 100 000 adults in the United States …

Chronic pancreatitis is defined as a pathological fibro-inflammatory syndrome of the
pancreas in individuals with genetic, environmental and/or other risk factors who develop …

Background and aim The International Cancer of the Pancreas Screening Consortium met in
2018 to update its consensus recommendations for the management of individuals with …

Since the discovery of the first trypsinogen mutation in families with hereditary pancreatitis,
pancreatic genetics has made rapid progress. The identification of mutations in genes …

Chronic pancreatitis describes a wide spectrum of fibro-inflammatory disorders of the
exocrine pancreas that includes calcifying, obstructive, and steroid-responsive forms. Use of …

Background & Aims Acute pancreatitis is characterized by premature intracellular activation
of digestive proteases within pancreatic acini and a consecutive systemic inflammatory …

A combination of genetic, environmental, and metabolic factors contribute to the
development and recurrence of acute and chronic pancreatitis; information on all of these is …

Chronic pancreatitis is an inflammatory disorder of the pancreas. We analyzed CPA1,
encoding carboxypeptidase A1, in subjects with nonalcoholic chronic pancreatitis (cases) …

Background Recurrent acute pancreatitis (RAP) and chronic pancreatitis (CP) are
associated with alcohol consumption and cigarette smoking. The etiology of RAP and CP is …

Abstract Background The American College of Medical Genetics and Genomics (ACMG)-
recommended five variant classification categories (pathogenic, likely pathogenic, uncertain …