Pediatric diffuse intrinsic pontine glioma (DIPG) represents approximately 20% of all
pediatric CNS tumors. However, disease outcomes are dismal with a median survival of less …

Simple Summary Medulloblastoma is the commonest malignant brain tumour of childhood.
Disease relapse following maximal multi-modal therapy including upfront craniospinal …

Purpose To report outcomes of salvage re-irradiation (re-RT) in recurrent/progressive
medulloblastoma (MB). Methods Medical records of patients treated with curative-intent re …

Background Diffuse intrinsic pontine glioma (DIPG) is a pediatric brain tumor with dismal
prognosis despite initial radiation therapy (RT). The clinical consequences of attempting …

Background Many studies have demonstrated in the last years that once medulloblastoma
has recurred, the probability of regaining tumor control is poor despite salvage therapy …

Radiotherapy is an essential element in the multidisciplinary management of children with
medulloblastoma and postoperative craniospinal axis radiotherapy is considered to be the …

Background Radiation necrosis is a frequent complication occurring after the treatment of
pediatric brain tumors; however, treatment options remain a challenge. Bevacizumab is an …

Since the development of new radiotherapy techniques that have improved healthy tissue
sparing, reirradiation (reRT) has become possible. The selection of patients eligible for reRT …

Aims Cancer remains a leading cause of death in children and adolescents in the
developed world. Despite advances in oncological management, rates of primary treatment …

Background We present our institutional approach for re-irradiation in diffuse intrinsic
pontine glioma and their outcomes. Methods Consecutive patients of recurrent diffuse …